Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

New intervention to protect lungs during cardiac surgery, feasible, safe, and effective, study finds
Medical Xpress / University of Bristol / Journal of the American Heart Association ^ | Sept. 27, 2024 | Raimondo Ascione et al

Posted on 10/01/2024 8:33:00 PM PDT by ConservativeMind

A new intervention which keeps lungs regularly expanding when using a heart-lung machine during heart valve surgery might protect lung function and exercise capacity in adult patients after the operation, a clinical trial has found.

The research could benefit similar patients globally undergoing cardiac surgery.

The aim of this randomized controlled trial was to find out if keeping the lungs regularly expanding, known as low frequency ventilation (LFV), during heart-lung machine in patients undergoing heart valve surgery could be linked to better postoperative lung function and exercise ability.

The study also wanted to find out the feasibility and safety of keeping lungs expanding during heart-lung machine, whether it affected surgery and if any specific change in biomarkers of lung injury could be identified and therefore targeted in future studies to develop a lung protection drug.

Current practice involves the lungs being left collapsed when using heart-lung machine during heart surgery, which is already known to trigger lung damage and reduced function after an operation. These complications are associated with a longer hospital stay and a greater risk of mortality in high-risk cases.

Sixty-three patients with severe mitral or aortic valve disease were randomized to either LFV or usual care with collapsed lungs. The average age of the patients was 66.8 years, 30% were women, and participants were followed up for six to eight weeks after discharge.

The trial found it was feasible and safe to use LFV when using heart-lung machine in patients undergoing heart valve surgery. In addition, it showed preserved lung function and patients walked significantly longer during the 6-minute walking test before discharge compared to those treated with usual care.

Also, LFV triggered a change to a specific biomarker/mediator (sRAGE) of lung function, which could be targeted in future studies.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: cardiac; lungs; medicalxpress; protect; surgery
Low frequency ventilation (LFV) appears to be a modification from current collapsing of the lung. It seems collapsing the lungs damages them, which would seem intuitively obvious, having both sides of lungs touching each other without normal pumping occurring.

This may be available as a current option worth exploring with your doctor.

1 posted on 10/01/2024 8:33:00 PM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 10/01/2024 8:33:33 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

.


3 posted on 10/01/2024 10:29:58 PM PDT by sauropod ("This is a time when people reveal themselves for who they are." James O'Keefe Ne supra crepidam)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Bkmk


4 posted on 10/02/2024 3:33:03 AM PDT by sauropod ("This is a time when people reveal themselves for who they are." James O'Keefe Ne supra crepidam)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Thanks for all your postings.


5 posted on 10/02/2024 7:36:14 AM PDT by goodnesswins (DEI....Divide, Enslave, Indoctrinate.....OR ......Didn't Earn It)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Had a collapsed lung occur during surgery. Not a picnic to recover from. 2 lungs must be pure hell. Must be one of the reasons a successful valve replacement surgery can still end up being fatal.


6 posted on 10/02/2024 6:35:20 PM PDT by The Westerner (Independent for Trump: 2016, 2020, 2024)
[ Post Reply | Private Reply | To 1 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson