Many years ago I read a book series where they developed an organism that ate oil to clean up the oceans. It did not end well.
Doorways (1993) was a proposed science fiction pilot that was never picked up. A mysterious alien feral woman appears on a freeway and after causing an accident with her weapon is taken to a hospital where she and the doctor that treated her eventually jump between alternate Earths to flee from the alien overlords who are chasing the alien woman.
They end up in a world where, 15 years ago, a microbe gene was created to clean up an oil spill, but it ate all petroleum in the world. They hitch a ride on a wagon (an Airstream trailer pulled by draft horses) with Jake (Hoyt Axton) and his granddaughter Cissy (Tisha Putman), who give them a ride to the nearest truck stop.The pilot is on Prime video, or video on the link which I started with the pair of protagonist are hitching a ride on the Airstream trailer.
Wikipedia: Pedler and Davis reused the plot of the first episode of the [British sci-fi t.v.] series [Doomwatch ], "The Plastic Eaters", for their 1971 novel Mutant 59: The Plastic Eater.
Regards,