Posted on 04/17/2024 5:16:44 PM PDT by DoodleBob
Wednesday, GSK plc (NYSE:GSK) revealed data from the ZOSTER-049 long-term follow-up phase 3 trial, which followed participants for up to approximately 11 years following initial vaccination with Shingrix (Recombinant Zoster Vaccine or RZV).
The final trial data demonstrate that RZV has maintained efficacy against shingles in adults over 50 for over a decade.
ZOSTER-049 included over 7,000 participants.
The results from ZOSTER-049, an extension from two phase 3 clinical trials in adults aged 50 and over (ZOE-50 and ZOE-70), include:
79.7% vaccine efficacy (VE) in adults aged ≥50 cumulatively from year six to year 11 after vaccination.
82.0% VE in adults ≥50 at year 11, showing VE remains high each year after vaccination.
73.1% VE in adults aged ≥70 cumulatively from six to 11 years after vaccination, showing high VE rates across all age groups.
Javier Díez-Domingo, Principal Investigator, said: “These final data demonstrate continued protection over more than a decade with high efficacy maintained in both the 50+ and 70+ age groups.”
GSK said it will continue to evaluate long-term data and conduct real-world evidence studies on vaccine efficacy, immunogenicity, and safety across indicated populations.
No new safety concerns were identified during the follow-up period in ZOSTER-049.
The investigators considered no serious adverse events causally related to RZV vaccination.
In adults aged 50 years and over, the most frequently reported adverse reactions with RZV are pain at the injection site, myalgia, fatigue, and headache. Most of these reactions were mild to moderate in intensity and generally lasted less than three days.
(Excerpt) Read more at msn.com ...
I’ve had shingles twice. Once I’m my 20s and once in my 60s. The first time I toughed it out. I had nerve twinges that lasted about 15 years. The second time I was prescribed valtrex and Gabapentin. The pain was completely gone in less than a day and no residual pain.
If you’ve ever had the shingles, you’ll wish you had the vaccine. If you haven’t got them yet you’ll wish you had the vaccine when you do.
Imagine the most intense burning nerve pain and then double it.
And then there’s the long lasting nerve damage after it subsides.
Do what you will but this is my humble advice.
I though that when a vaccine was “effective”, it meant that you still got the illness but it was hypothetically less severe?
What changed?
Not really. A vaccine is supposed to work like the polio vaccine works. I had mine some 70 years ago, and it's still effective.
I would have to be in the morgue for ANY vaccine of ANY kind to be put into my arm I don’t trust these bastards!!! I have had ONE vaccine in my life and that was smallpox, caught ALL of the diseases as they came through AND my immune system worked as God intended!!!
In other words, PREVENTION.
Let's look at the actual FDA and Pfizer-BioNTech info.
On August 23, 2021, the FDA approved the first COVID-19 vaccine. The vaccine has been known as the Pfizer-BioNTech COVID-19 Vaccine, and will now be marketed as Comirnaty, for the prevention of COVID-19 disease in individuals 16 years of age and older.(emphasis added)
Per the Comernity Insert,
--------------------------- INDICATIONS AND USAGE----------------------------
COMIRNATY is a vaccine indicated for active immunization to prevent coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 16 years of age and older. (1)(emphasis added>
Per the Summary Basis for Regulatory Action, under "Indication"
Active immunization to prevent coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 16 years of age and older. (Emphasis added)
Clearly, the sjots for Covid were for PREVENTION. Nothing else. All of the clinical trials (limited as they were) and statistical confidence intervals were focused on Vaccine Efficacay (VE) with regard to PREVENTION...not hospitalization, not ER visits, and not symptoms. Accordingly, THAT is the basis upon which VE should be evaluated.
What “changed” was the narrative. Once VE started collapsing over time, necessitating endless boosters, the press and the pharmaceutical-industrial complex started chatting about “reduced incidence of hospitalization, bad cases of Covid, and death.”
And sure, maybe that happened statistically. But that’s not what the clinical trials were designed to test. Indeed, the FDA goes hard after vitamin and homeopathic products if they even THINK of claiming some benefit that’s not part of their approval package. But the Covid shots? Heck, they can stop world hunger.
Let me be clear: any shot has side effects. Being a fully-informed customer and patient is a matter of life and death nowadays.
I am not promoting the shingles vaccine. What I AM promoting, is the difference between a product that works as expected and for a sustained period of time, and a lie.
That is the real issue here.
Shingles was the single most traumatic event of my life.
7 weeks of hell.
Get that vax.
myself, my wife and many friends all had very mild cases of shingles, as is the case with most people ...
additionally, the fraudulent medical community continues to claim that there’s no natural immunity gained from contracting the shingles, and that only a synthetic vaccine will convey immunity against the shingles ... JUST LIKE COVID! ... remember, there’s no such thing as natural immunity!
“She said the pain was so bad she wanted to die. It lasted for months.”
Same here.
It will cause you to contemplate suicide.
My health took a big hit. I’m recovering but it’s slow and it hurts. I think the VA is gonna give me a new hip. Then some oral surgery, then the shingles shot. It’s two shots some time apart. Folks say one or the other is gonna kick your ass so I’m really looking forward to it. Ivermectin at the ready.
This is interesting to me. I have a sister who had shingles about 20 years ago. She is under high stress did not get the Covid vaccine and they told me last week that she was going to get this shingles vaccine. So she went to Publix and got it. Came over to my house. The other day said her arm hurt really bad. Called me up at night. Said she was really sick but so was her husband. They went to the doctor and got meds for whatever they have, mainly sinus.
This morning at 4 o’clock she texted me saying she has shingles. She told me that the only person that they have on record that got shingles from the vaccine is a 73 yo woman with a weak immune system. My sister is a 73-year-old woman with a kidney transplant 40 years ago.
I had shingles maybe 12 years ago, not sure. Got it on my face in my eye, I have scars, it is not something to be trifled with.
They say it comes from having had chickenpox as a child and not being around children for a long time with chickenpox. We used to get immunity storm and the kids but now the kids all have had vaccines, that’s what I heard.
It’s not new and it’s not mRNA.
the reason people get shingles in the fist place is because there is very little chickenpox in the wild.
I am looking for a pox party so I can be exposed again and my immune system will be recharged and I will never get shingles.
did anyone else notice the huge increase of shingles when people started getting jabed, and their immune systems getting overwhelmed with spike proteins ?
Thank you. My Dad had what his doctor described as the "worst case of shingles he had ever seen". He had to take opiates for 10 years to deal with the pain. So, I need to give this vax serious consideration as long as I'm reasonably certain it's not adulterated or "experimental".
I am never getting another shot as long as I live.
Same.
There is indeed a world of difference.
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