I assume losing weight on your own could help similarly, though.
There is some risk. SGLT2 has also been associated with major adverse events, including diabetic ketoacidosis in type 1 diabetes patients and limb amputations and genital and urinary tract infections in type 2 diabetes patients. The use in type 2 diabetes patients with cardiovascular disease, renal disease, or heart failure has been established in several large trials. Of concern are the increased risks of lower-limb amputation and bone fracture, diabetic ketoacidosis, acute kidney injury (AKI), serious urinary tract infections, and—more recently—Fournier gangrene (necrotizing fasciitis of the perineum). This study was done in 2018/19 by:
Ryan J. Sangiovanni, PharmD
Assistant Professor of Pharmacy Practice
Presbyterian College School of Pharmacy
Clinton, South Carolina
Carley E. DeVee, PharmD, BCPS
Assistant Professor of Pharmacy Practice
Presbyterian College School of Pharmacy
Clinton, South Carolina
So in a perfect world there are inperfections.
wy69
One dose of Jardiance made my brain go crazy.
Not taking another ever.
I take one of these, and it reduces glucose ;evels, reduces insulin dose and gradually allows one tio lose weight.
I take Dapagliflozin. No side effects after one month, dropped about 10 pounds.
I recommend it for anyone with type II diabetes with A1C readings over 7.5 ( 139 ).
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I’ve read reviews from users on these type of drugs, like Jardiance, et al. There can be some serious side effects. Be cautious.
Start with krill oil and lots of distilled water every day first, you might be amazed at the results.
Having issues getting my Trijardy (metformin, Jardiance, Trajenta combo) refilled this week, looks like we’re competing with the dieters now.