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How gum disease aggravates chronic obstructive pulmonary disease
Medical Xpress / American Society for Microbiology / mSystems ^ | Jan. 12, 2024 | Boyu Tang, Ph.D. et al

Posted on 01/15/2024 10:02:41 PM PST by ConservativeMind

Severe gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding remains unclear.

Researchers report that bacteria associated with the gum disease promote COPD through the activation of two types of cells, γδ T cells and M2 macrophages, that are important to the immune system.

"By enhancing periodontal therapy and targeting the inhibition of γδ T cells and M2 macrophages [we] may be able to help control the progression of COPD," said Boyu Tang, Ph.D.

Periodontitis is a gum disease that results from the untreated buildup of plaque, a sticky film of bacteria. Over time, the plaque can harden into tartar and cause irritation and inflammation of gum tissue, and then produce deep gaps between the teeth and gums where bacteria flourish and may lead to bone loss. Previous studies have found that it's a risk factor for a raft of diseases, including diabetes, hypertension, some cancers, cardiovascular disease and COPD.

Studies have established that the oral bacteria Porphyromonas gingivalis plays an important role in gum disease. For the new work, Li, Tang and their colleagues used mouse models to show how those bacteria could aggravate progression of COPD. In one experiment, they showed that mice infected with both periodontitis and COPD had worse progression of COPD.

In another experiment, they found that in mice orally infected with P. gingivalis, the bacteria migrated to and infected lung tissue, leading to a significant, observable change in the lung microbiota. Further observations using flow cytometry and immunofluorescence revealed that periodontitis promoted the expansion of the immune cells in the lung tissue.

Finally, in experiments using mouse lung tissue, the group connected the dots by showing that P. gingivalis could activate the immune cells, promoting their ability to produce cytokines associated with worsening COPD.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: copd; gumdisease
It seems bacteria migrate to the lungs and cause a persistently elevated immune reaction that further hurts the lungs.

It would seem eliminating bleeding gum issues and having antibiotics to eradicate such bacteria could be helpful.

1 posted on 01/15/2024 10:02:41 PM PST by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 01/15/2024 10:03:11 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Xylitol


3 posted on 01/15/2024 10:10:49 PM PST by kiryandil (Rocco is roccking again!!)
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To: ConservativeMind

A couple of months ago I began swishing a silver solution around in my mouth after brushing my teeth. I have a dentist appt. in March and can’t wait to find out if it’s doing any good.


4 posted on 01/15/2024 10:13:03 PM PST by ryderann
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To: ryderann

My gums used to bleed when brushing, flossing, or using a toothpick. All that stopped after I went on the carnivore diet.


5 posted on 01/15/2024 10:58:24 PM PST by JohnnyP (Thinking is hard work (I stole that from Rush).)
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To: ConservativeMind

The Pros and Cons of Deep Cleaning Teeth

https://www.healthline.com/health/deep-cleaning-teeth


6 posted on 01/16/2024 1:09:56 AM PST by Libloather (Why do climate change hoax deniers live in mansions on the beach?)
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To: ConservativeMind

.


7 posted on 01/16/2024 3:29:55 AM PST by sauropod (The obedient always think of themselves as virtuous rather than cowardly.)
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To: ConservativeMind

Yep - the bacterial infections from rotten teeth/gums can kill a person - and let’s face it - viral pneumonia isn’t nearly as deadly as bacterial pneumonia....


8 posted on 01/16/2024 5:29:50 AM PST by trebb (So many fools - so little time...)
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To: ConservativeMind

Don’t ignore gum disease. It can also cause heart issues.

If you can’t get your gum disease under control, remove your teeth. Seriously.


9 posted on 01/16/2024 6:50:24 AM PST by GrannyAnn ( )
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To: ConservativeMind

Maritime Pine Bark.

Google the benefits on mouth bacteria, blood, etc.


10 posted on 01/16/2024 7:13:54 AM PST by aMorePerfectUnion
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To: ryderann

Here is what worked extremely well for me: Put a half capful of Listerine into the Waterpik tank, then use the waterpik on a low setting. Clears up any tenderness or infection in a few days. Once a day keeps it away.

Went from always expecting bleeding gums at the dentist to never having any gum pain at the dentist.


11 posted on 01/16/2024 7:48:06 AM PST by Mr Rogers (We're a nation of feelings, not thoughts.)
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To: Libloather

Thanks for posting that link. I had this done, just yesterday! I look like a chipmunk today. Not fun but glad to do it.


12 posted on 01/16/2024 8:13:35 AM PST by LittleBillyInfidel (This tagline has been formatted to fit the screen. Some content has been edited.)
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