Pretty much common sense. For essentially everything, the poison is in the dose. If I eat one almond per day for 1,000 days, I’ll be just fine. If I eat 1,000 almonds in one day, I have a good chance of dying from the naturally occurring cyanide in almonds.
If you weigh 180 lbs and you consume a maximum of ten 12 oz. beers @ 4.x % alcohol content and you space them at least 40 minutes apart with intermittent food, I don’t think your liver is going to be scarred for life, especially if you’re a nonsmoker. Keeping hydrated can lessen the after-effects and if you can train yourself to limit that routine to 2-3 times a month, then I don’t think you’re going to be on any sort of slippery slope except if you’re a regular at one or more of your local local watering holes and insist on driving yourself around. I’m not a doctor, so this is all speculation on what MADD, AA and others in their “field” may not want you to know.
I saw my father-in-law die of cirrhosis after a lifetime of alcohol abuse. From what I’ve read, I’d take crucifixion over cirrhosis in a heartbeat. Cirrhosis is a fiendishly hellish way to die very slowly.
I thinks it’s genetics period.