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To: ConservativeMind

Yeah, it isn’t new news. I did a trial with it about five years ago and couldn’t tolerate even 250 mg. And among diabetics it has a pretty high failure rate due to adverse effects.


3 posted on 10/15/2023 8:40:12 PM PDT by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: steve86

I’ve heard similar stories. My wife, however, is a type 2 diabetic and does very well on metformin (1000mg daily).


5 posted on 10/15/2023 8:48:29 PM PDT by Spacetrucker (George Washington didn't use his freedom of speech to defeat the British - HE SHOT THEM .. WITH GUNS)
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To: steve86

That’s too bad given it’s inexpensive. Seems to work my family


6 posted on 10/15/2023 8:51:52 PM PDT by Gene Eric (Don't be a statist!)
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To: steve86
Yeah, it isn’t new news. I did a trial with it about five years ago and couldn’t tolerate even 250 mg. And among diabetics it has a pretty high failure rate due to adverse effects.

Can you document the failure rate?

I've been using it for 45 years. Started with 250 mgs/day in late 1970s and was up to 4 500 mgs per day--never a sign of a problem.

Backed off to 3 500s/day since 2000 mgs is usual daily limit according to my MD.

Sorry to hear you had a problem with it--metformin is a truly remarkable medicine.

8 posted on 10/15/2023 10:37:09 PM PDT by henbane ( )
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To: steve86

Many people do better with the extended release metformin.


15 posted on 10/16/2023 6:23:12 AM PDT by Roos_Girl (The world is full of educated derelicts. - Calvin Coolidge)
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