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2 posted on 08/31/2023 8:20:20 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I had to look up to find the drugs in each class:

Warfarin, the most frequently used oral VKA in the United States, inhibits the vitamin K-dependent carboxylation of coagulation factors II, VII, IX, and X and proteins C and S.

There are currently four NOACs available for patients with atrial fibrillation: dabigatran (Pradaxa®), rivaroxaban (Xarelto®), apixaban (Eliquis®), and edoxaban (Lixiana [Europe/Asia], Savaysa [Nth Am]. NOACs are the first-line treatment for most patients with venous thromboembolism (VTE) and for stroke prevention in atrial fibrillation (AF). NOACs have a lower propensity for drug and food interactions compared to vitamin K antagonists (VKAs) due to their individual coagulation proteins target and to the administration in fixed-dose without requiring routine coagulation monitoring.

Note that Vitamin K2 and D3 are essential for keeping calcium in the bones and out of the blood vessel walls, so a Vitamin K antagonist might not be a good thing for older patients.


3 posted on 08/31/2023 8:52:06 PM PDT by SubMareener (Save us from Quarterly Freepathons! Become a MONTHLY DONOR)
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