I had to look up to find the drugs in each class:
Warfarin, the most frequently used oral VKA in the United States, inhibits the vitamin K-dependent carboxylation of coagulation factors II, VII, IX, and X and proteins C and S.
There are currently four NOACs available for patients with atrial fibrillation: dabigatran (Pradaxa®), rivaroxaban (Xarelto®), apixaban (Eliquis®), and edoxaban (Lixiana [Europe/Asia], Savaysa [Nth Am]. NOACs are the first-line treatment for most patients with venous thromboembolism (VTE) and for stroke prevention in atrial fibrillation (AF). NOACs have a lower propensity for drug and food interactions compared to vitamin K antagonists (VKAs) due to their individual coagulation proteins target and to the administration in fixed-dose without requiring routine coagulation monitoring.
Note that Vitamin K2 and D3 are essential for keeping calcium in the bones and out of the blood vessel walls, so a Vitamin K antagonist might not be a good thing for older patients.