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Oral probiotic shows promise for treating dry eye disease in mouse study (L. reuteri)
Medical Xpress / ASM Microbe 2023 / Annual meeting of the American Society for Microbiology ^ | June 18, 2023 | Laura Schaefer, Ph.D. et al

Posted on 06/20/2023 7:49:15 PM PDT by ConservativeMind

In a study, oral administration of a commercially available probiotic bacterial strain was found to improve dry eye disease in an animal model.

Dry eye, a common condition in which tears produced by the eye can't keep the eye adequately lubricated, afflicts approximately 1 in 20 people in the United States. It can cause eye stinging and burning, inflammation, blurry vision and light sensitivity.

Laura Schaefer, Ph.D. said, "The 'friendly' bacteria that live in the human gastrointestinal tract have been linked to health and protection against disease in many parts of the body, including the gut, brain, and lung. It's therefore not surprising that the gut microbiome also has effects on our eyes."

One possible treatment avenue for dry eye would involve probiotic bacteria that have similar protective effects. The group investigated this by using an orally administered probiotic bacterial strain, Limosilactobacillus reuteri DSM17938, in a dry eye mouse model. DSM17938 is a human-derived, commercially available probiotic bacterial strain that has already demonstrated protective effects in the gut and immune system in humans and mice, but it has not been tested in the context of eye health.

Mice were first treated with antibiotics, which kills many of the "friendly" bacteria living in the gut. They were then exposed to very dry conditions and fed daily doses of either probiotic bacteria or a saline solution as a control. After 5 days, the eyes were examined for disease.

The mice that were fed the probiotic bacteria had healthier and more intact corneal surfaces. In addition, these mice had more goblet cells in their eye tissue, which are specialized cells that produce mucin, an essential component in tears. Taken together these data suggest that the right oral probiotic could help treat and manage dry eye symptoms.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: donateforjim
The substrain of reuteri is L. reuteri DSM 17938, which is available in the BioGaia Protectis probiotic supplement.

It is possible its mother strain, the more common form of L. reuteri, could provide similar benefits, though.

1 posted on 06/20/2023 7:49:15 PM PDT by ConservativeMind
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2 posted on 06/20/2023 7:49:52 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

What about other strains of probiotic bacteria?


3 posted on 06/20/2023 7:52:37 PM PDT by EinNYC
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To: ConservativeMind

Is the BioGaia Protectis probiotic supplement you noted the stuff they give colicy babies?


4 posted on 06/20/2023 7:56:30 PM PDT by Obadiah
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To: ConservativeMind

This is good news, I just saw a field mouse eating my chicken food and he looked like he had dry itchy eyes.

I hope it’s not an injection I’ll have to give him.


5 posted on 06/20/2023 7:59:30 PM PDT by Sarcazmo (I live by the Golden Rule. As applied by others; I'm not selfish.)
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To: Sarcazmo

Oh!! It’s oral, thank the heavens. I should have read the title better!


6 posted on 06/20/2023 8:00:47 PM PDT by Sarcazmo (I live by the Golden Rule. As applied by others; I'm not selfish.)
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To: ConservativeMind
In the name of Sam Hill, just eat yogurt, kimchi, sauerkraut, and anything else fermented. People have known this for ages.
7 posted on 06/20/2023 8:06:35 PM PDT by Fungi
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To: Fungi

kefir, kraut and homemade pickles.


8 posted on 06/20/2023 8:08:39 PM PDT by MomwithHope (Forever grateful to all our patriots, past, present and future. )
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To: EinNYC

No others were noted to help.


9 posted on 06/20/2023 8:10:21 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Obadiah

Actually, yes!


10 posted on 06/20/2023 8:11:07 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Bookmark


11 posted on 06/20/2023 11:54:22 PM PDT by Irish Eyes
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To: ConservativeMind

You can probably buy a small batch and multiply it with a yogurt maker. Here is someone doing it: https://www.luvele.com.au/blogs/recipe-blog/new-improved-l-reuteri-yogurt-method

According to the following study, the growth of L. reuteri DSM17938 in milk is increased by the addition of S. thermophilus and L. delbrueckii by roughly three times versus the growth of L. reuteri DSM17938 in milk by itself. Those other two strains are supposed to be present in traditional yogurt cultures, so I’m hoping that it shouldn’t be too difficult to reproduce this concoction at home. Go to page 21: http://stud.epsilon.slu.se/5988/1/karlsson_m_130828.pdf

This exact L. reuteri DSM 17938 from BioGaia was in the news a few years ago for making people “younger looking” — probably by improving the skin. This article says it boosts collagen: https://www.fiftyish.com/style/yogurt-for-wrinkles


12 posted on 06/21/2023 1:27:14 AM PDT by UnwashedPeasant (The pandemic we suffer from is not COVID. It is Marxist Democrat Leftism.)
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