New test reveals existing antibiotics, hiding in plain sight on pharmacy shelves, can cure superbugs

Medical Xpress / University of California - Santa Barbara / Cell Reports Medicine ^ | April 27, 2023 | Shelly Leachman / Douglas M. Heithoff et al

[ConservativeMind]

A new test revealed that FDA-approved antibiotics—available at your neighborhood pharmacy—can effectively treat superbugs. They are not prescribed, however, because the gold-standard test predicts they will not work. The new test may improve the way antibiotics are developed, tested and prescribed—and it is openly available to all.

The research has significant implications in the fight against bacterial resistance by optimizing the prescription and use of currently available antibiotics and enhancing the efforts to discover new ones.

Developed by a research team, the antibiotic study addressed a fundamental flaw in the healthcare paradigm for determining antibiotic resistance. It does not account for environmental conditions in the body that impact drug potency.

By simulating conditions in the body, the new test identified several effective antibiotics rejected by standard testing. Further, when the new and standard tests agreed—a nearly perfect prediction of treatment success or failure was observed.

The study required a tour de force screening of more than 500 antibiotic-bacteria combinations. The findings suggest that the standard test is incorrect ~15% of the time. And since physicians rely on this test for treatment decisions—it may lead to prescription of the wrong antibiotic.

"People are not Petri plates—that is why antibiotics fail," said Mahan. "Testing under conditions that mimic the body improves the accuracy by which lab tests predict drug potency."

Physicians are aware of the flaws in the gold-standard test. When recommended antibiotics do not work, they must rely on their experience to decide on the appropriate antibiotic(s) for their patients.

This study provides a potential solution to address the disparity between antibiotics indicated by standard testing and actual patient outcomes.

[minnesota_bound]

Ivermectin and HCQ would prevent the chinese virus but the democrats blocked their use. Many people died and thanks to the deadly vaccine those remaining are either dead or crippled or have other diseases because the immune system is compromised.