Posted on 03/30/2023 8:56:57 PM PDT by ConservativeMind
For patients with nonsegmental vitiligo, continued improvement in seen during a long-term extension of ruxolitinib treatment.
Noting that ruxolitinib cream demonstrated facial and total body repigmentation over 52 weeks in two phase 3 vitiligo studies (TRuE-V1/TRuE-V2), David Rosmarin, M.D. and colleagues examined shifts in facial/total Vitiligo Area Scoring Index (F-VASI/T-VASI) responses over an additional 52 weeks of open-label ruxolitinib treatment among patients aged ≥12 years who did not achieve ≥90 percent improvement in F-VASI (F-VASI90) at week 52.
The researchers found that 66.1 percent of the 222 patients initially randomly assigned to ruxolitinib achieved F-VASI75 at week 104, up from 30.8 percent at week 52 and 54.6 percent at week 80; a corresponding increase in T-VASI50 was seen, from 42.5 and 57.7 to 63.8 percent. At week 104, 30.9 percent attained F-VASI90. At week 80, 36.2 and 47.1 percent, respectively, remained stable and had improvement in F-VASI responses attained at week 52; 51.1 and 31.7 percent, respectively, remained stable and had improvement in T-VASI responses attained at week 52. Compared with results attained at week 80, at week 104, 64.4 and 19.6 percent, respectively, remained stable and had improvement in F-VASI responses, while 61.3 and 22.2 percent, respectively, remained stable and had improvement in T-VASI responses.
"Vitiligo is a chronic condition and these results demonstrate the long-term potential of this medical treatment for people with vitiligo who are interested in repigmentation," Rosmarin said in a statement.
(Excerpt) Read more at medicalxpress.com ...
This drug is also known as Jakafi.
Self-ping. I have it on my hands and it doesn’t bother me after I got used to it. I do see some specks on my neck so that sort of sucks.
Although my daughter told me “Dad - if people don’t like you because you have some spots on your face, do you really want them for friends anyway?”
But if using a simple cream can keep it at bay, what the heck. The doctor gave me some cream early on but it didn’t work. He said there were two types of vitiligo, one was caused by a fungus that could be treated with cream - the other not.
Its not clear to me what this condition is and how many people have it.’
Can you flesh out this story a bit?
Oh wait a minute.
This refers to people with those wierd light spots on their faces.
I may have seen that once or twice on the faces of people in the crowd over the last dozen years or so.
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