The other issue is that you could be walking around with genetic defects in your IL1B gene that make you susceptible to things like Antisynthetase system.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732678/
Tinkering around with the IL1b gene might trigger something bad...or it might be possible that it would help. Anyone that has one of the components of Antisynthetase might check what their Dr has to say
there was a previous thread about glutamate.
https://selfhack.com/blog/interleukin-1/
“Evidence suggests that IL-1 can potentiate or inhibit the effects of glutamate. IL-1b causes “synaptic hyperexcitability” and neuronal degeneration [40]. This isn’t conducive to stable thinking.”