A doctor who the late Mrs. Chajin saw over a decade ago was reasonably well-versed in Dr. Amen’s brain studies. The doc was convinced that one of the major neurochemical issues was the accumulation of glutamate in the brain, and recommended liposomal glutathione to remove the excess glutamate. He didn’t say anything about it affecting the tendency to obesity, but it would be interesting if that were an additional benefit.
Low dose naltrexone is suppose to help with the glutamate issue.
You should check into Dr Christopher Palmer’s work in brain metabolism and treatment of psychiatric disorders by correcting metabolic disorders.
https://www.youtube.com/live/WjY_pmIyXnw?feature=share
Interview starts about 20 minutes in.