Basically it says, if your body is chronically exposed to an antigen, then your body switches from antibody IgG1 to IgG4 (changes from 'wipe the invader out' to 'eh, big deal') to deal with it; and overall, you get a LOT more IgG4 than your body is supposed to have...with a lot of possible side effects . You know, like cancer.
“IgG4 class switching is associated with chronic exposure to antigen. This particular subclass of antibody can outcompete other antibody species, like IgG1, to subsequently block their effector mechanisms. One of these effector mechanisms imposed by IgG1 is tumor control (or suppression), mediated by antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP) and complement-dependent cytotoxicity (CDC). These mechanisms are all ways to keep unwanted cells and material under control. (As in, IgG1 is the portion of our immunity that sweeps for cancer. If IgG4 suppresses IgG1, then tumor cells can grow out of control). In yesterdays post, we saw that IgG1 dropped with each additional vaccine.
So those three ways: the ADCC, ADCP and CDC - that aid in removal of unwanted cells are all nullified in the scenario where IgG4 is prevalent. Worse than that, since the subclass switch is literally the by-product of continuous antigen stimulation, then this is an immunological endorsement of a ‘win’ for IgG4 if we consider competition for binding sites. In effect, IgG4 outcompetes IgG1 and thus, the scales tip from tumor suppression, to tumor progression. All because of IgG4. Now I don’t want to scare everyone, but persistent re-injection of a messenger RNA that encodes a foreign, highly immunogenic protein, is NOT a good idea in this context. This is precisely continuous antigen stimulation by spike protein. Not only that, since we know that both the mRNA and the spike protein are long-lasting in the body, you mightn’t even have to re-inject yourself repeatedly qualify as undergoing continuous antigen stimulation. In fact, I would bet that this would be a given. Furthermore, I would bet that due to this continuous antigen stimulation, the IgG1:IgG4 subclass ratio is inverted in people who are persistently making spike, and that these people would be subject to cancer promotion, rather than suppression.
Looks like someone was alleging monkey business with ongoing VAERS reports.
https://jessicar.substack.com/p/the-foreign-data-set-was-gutted-this
IgG4 (Iggy-4) keeps popping up.