Posted on 12/17/2022 8:35:10 PM PST by ConservativeMind
According to recent estimates, over 140 million people from 50 countries regularly get exposed to arsenic through drinking water. It is an established fact that chronic arsenic exposure from drinking water causes a variety of cancers including skin cancer.
Researchers have recently been able to identify the underlying biological mechanisms of carcinogenesis inhibition. Using in vitro studies, the research team has been able to demonstrate how calcitriol, or activated vitamin D3, inhibits arsenic-mediated carcinogenesis in certain types of skin cells known as "keratinocytes."
Quite interestingly, arsenic levels in HaCaT cells cultured with arsenic significantly decreased when these cells were treated with increasing doses of calcitriol.
Dr. Masashi Kato adds, "Calcitriol significantly repressed arsenic uptake in HaCaT cells with the regulation of expressions of aquaporin genes (AQP7, 9, and 10), which were modified by arsenic exposure. Vitamin D receptor expression was significantly increased by arsenic exposure whereas calcitriol had no effect on the expression of the receptor."
Prof. Yajima says, "These results suggest that calcitriol suppresses arsenic-induced tumorigenesis not only in keratinocytes, but also in other target cells including lung epithelial cells. We therefore believe that activated vitamin D3, or calcitriol, may contribute to the prevention and therapy for arsenic-mediated diseases including cancer."
Environmental toxins such as arsenic contribute significantly to the development of life-threatening diseases such as cancer. However, it may take years, even decades, for cancer to develop from drinking arsenic-contaminated water. The current research clearly indicates that calcitriol could be used as a test compound for validating the safety and efficacy of activated vitamin D3 and/or its analogs in preventing or treating arsenic-triggered cancer.
Taking vitamin D3 beforehand in arsenic-contaminated areas may reduce the risk of cancer development 5 or 10 years later and help people maintain good health for a long time.
(Excerpt) Read more at medicalxpress.com ...
This result seems too specialized for general interest. Calcitriol, the active form, is much more dangerous that vitamin d. Even reading a lot of publications about it people here probably won’t be able to judge whether it might benefit them or use it safely.
A doctor would have to prescribe it, anyway, if it was calcitriol.
I don't understand your concern.
I buy filtered and purified water at Natural Grocer. Like Natural Grocer, many stores have gallon or 5-gallon refillable plastic bottles. Our water is so terrible I won’t even give it to my cat.
You can look up. your zip code at ewg.org water data base. Ours has 10 contaminants and we have lead in our pipes.
I’ve always preferred prevention rather than cures.
Vitamin D is a master hormone and is involved in thousands of processes in the body.
G
Most of those areas get lots of sun. No lack of regular vitamin D
I have been taking D3 since the first few months of the Covid thing but I have wondered if I’m getting it in the right form. Absorption or the lack thereof is critical.
Not a problem here, but in countries like Bangladesh, almost ALL the groundwater has high arsenic levels.
Liquid form may be worth a try, and remember you need Vit K with D3
Also...have you been tested?
Well...THAT is interesting...EWG.ORG
Vitamin D supplements are a great idea for most people. We don’t get enough sun.
As have I and my doctor asked me to cut my intake in half from 5,000iu to 2,500iu. My wife takes care of our 11 month grandson who had a bad cold. She got sick but I didn’t and I handled him as well.
A lot of people are very enthusiastic about taking vitamin d. It’s possible to take too much. It’s good to know that doctors are careful to not take too much.
For a long time, people in the coldest countries took 10 micrograms per day. Your new dose is about 60 micrograms per day.
D3 plus K2. K2 makes sure the D3 gets absorbed right and into the right places. Otherwise it can end up in muscles/soft tissues and bind with calcium.
I asked my doctor about vitamin K once and he specifically told me for whatever reason to not take K supplements.
Do you still have the same doc?
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