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Let the patient choose their type 2 diabetes medication, says study
Medical Xpress / University of Exeter / Nature Medicine ^ | Dec. 7, 2022 | Beverley M. Shields et al

Posted on 12/08/2022 9:55:38 PM PST by ConservativeMind

A large-scale new study offers a new approach to treating in type 2 diabetes, one that puts patients in charge of their own medication. The Trimaster study is the first to allow people with type 2 diabetes to choose their own medication, after trying three different drugs in succession. It concluded the approach could be a new way of finding the best treatment.

Researchers gave people with type 2 diabetes three commonly-prescribed drugs, each for a 16-week period in turn. Researchers monitored the effect of each drug on the 448 patients' glucose levels, weight and recorded the side effects.

At the end of the study, patients got to choose the drug that worked best for them. Their chosen drug not only lowered glucose most effectively, but also resulted in fewer side effects.

Dr. Beverley Shields said, "Interestingly, we found that the treatment people chose was usually the one which gave them best blood sugar control—even before they knew those results."

Participant Tim Keehner was diagnosed with type 2 diabetes 15 years ago.

"I was given three drugs. The first two didn't work for me at all—in fact, one of them made me feel even worse. Thankfully, from the first moment I took the third drug, I felt different—I had more energy, and I knew it was the right drug for me. I'm still on it today and I'm able to engage in all the sports I love—it's fantastic."

"We've shown that going with the patients' choice results in a better glucose control and fewer side effects than any other approach. When it's not clear which drug is best to use, then patients should try before they choose. Surprisingly, that approach has never been tried before."

The three drugs given to patients in the trial were sitagliptin, canagliflozin, and pioglitazone.

(Excerpt) Read more at medicalxpress.com ...


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To: DallasGal

I’m also on the road to getting off all diabetes meds.

My Dr referred me to this guy from Canada. Funny little voice but I’m already wrecking my high glucose numbers.

https://www.dietdoctor.com/authors/dr-jason-fung-m-d

Basically I eat a late breakfast and am done with dinner by 7. No snacking.
I have not completely removed sugars and carbs but have cut them down substantially.

Only about 10 days in and my fasting sugar ##’s down from the 170-180 range to 130-140. Already had one morning at 103.

Here’s a short YouTube from the same guy that kicked it off for me.

https://youtu.be/ED8VtvRFr_I


21 posted on 12/09/2022 8:31:24 AM PST by jcon40 (Machinery is only as good as its design and quality of parts. A citizen is only as good as...)
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To: nitzy
Do you know what I call a doctor who finished in the bottom 5% of her class in Medical school?...

I don't.

22 posted on 12/09/2022 10:33:11 AM PST by higgmeister (In the Shadow of The Big Chicken!)
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To: DallasGal

How are your numbers looking, now?


23 posted on 04/02/2023 9:24:20 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: jcon40

How is keto working for you?


24 posted on 04/02/2023 9:27:50 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Good Thank You. Just had a 7.3 A1C but new doc says that’s fine looking at my history.

How’s your sweet tooth?


25 posted on 04/03/2023 10:51:44 PM PDT by jcon40 (Most Leftists are just suckers shouting nonsense prepared by crafty, self serving exploiters )
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To: Doofer
I can't eliminate all carbs....so I just don't eat sweets or juice and try to eat bread, rice, pasta, potatoes infrequently...

you know what I miss the most?....morning cereal....my cheerios knock off was so good.

26 posted on 04/03/2023 10:56:53 PM PDT by cherry
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To: jcon40

Thankfully, my numbers for blood sugar and A1c are in the normal range, but at the high end.

I need to move more than I do! Also, just in the last month, we picked up some chocolate dipped freeze-dried fruits, and, unfortunately, I’ve had days of more than my expected two pieces, but I don’t have other carbs, of consequence, thankfully.


27 posted on 04/03/2023 10:58:19 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: DallasGal

moderation in all things....I can eliminate most carbs but I do like to have an apple...


28 posted on 04/03/2023 10:58:54 PM PDT by cherry
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To: ConservativeMind

Hope those are dark choc dipped ? Unfortunately I eat a lot of coated nuts w quality dark choc. There are keto chocolates that are fairly good.

I’ve added pomegranate juice to my daily habits. Interesting research there. Oh, and my Keto-ing I’m doing intermittently.

Talked to my new doc about consistent high fasting numbers in the AM (140-160). He has me doing a small non carb or sweet snack close to laying down and seems to help. Thought that an odd suggestion. He’s also ok with some ice cream provided its good ingredients.


29 posted on 04/03/2023 11:21:17 PM PDT by jcon40 (Most Leftists are just suckers shouting nonsense prepared by crafty, self serving exploiters )
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To: ConservativeMind

>> I need to move more than I do! <<

A friend showed me an exercise / stretching trick where you grab the rim of the kitchen sink, do squats, stretching, girly pushups with feet and hands in different positions. Also side to side movement.

So now I have a new relationship with my kit sink.


30 posted on 04/03/2023 11:28:59 PM PDT by jcon40 (Most Leftists are just suckers shouting nonsense prepared by crafty, self serving exploiters )
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To: jcon40

It in Ketosis, I, too, get higher glucose levels, around 108. It is the body temporarily refusing to use liver-generated carbs. It goes away by late morning, and is common.

However, you are coming from a different angle.


31 posted on 04/04/2023 6:05:52 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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