Is it possible to open door in flight?
Before it is pressurized, yes. But still not a good idea to try.
From what I’ve read - the cabin pressure won’t allow the door to be opened.
“Once airborne, a pressurized aircraft’s doors can not be opened. This is true for pilots, flight attendants, and passengers. Why? For the simple reason that cabin pressure won’t allow it.”
https://simpleflying.com/can-aircraft-doors-be-opened-in-flight/
It would still scare the hell outta me though.
A few weeks ago I went skydiving for the second time. It was a tandem jump so I was connected to my instructor. A sport jumper deplaned at a lower altitude so my job was to close the airplane door in flight.
It was a roll up, like a garage door. Unpressurized aircraft of course.
No, you cannot.
Did the flight attendant then get a rabies shot?