https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221828
“Here, we show that inulin increases beneficial microbiota and decreases harmful microbiota in the feces of young, asymptomatic APOE4 transgenic (E4FAD) mice and enhances metabolism in the cecum, periphery and brain, as demonstrated by increases in the levels of SCFAs, tryptophan-derived metabolites, bile acids, glycolytic metabolites and scyllo-inositol. We show that inulin also reduces inflammatory gene expression in the hippocampus. This knowledge can be utilized to design early precision nutrition intervention strategies that use a prebiotic diet to enhance systemic metabolism and may be useful for reducing AD risk in asymptomatic APOE4 carriers.”
My question is…..how much inulin we’re given to the mice over a two week period.
Was it a total amount that a normal person would consume in a life time?
Or, wast it 10x the amount a normal person would eat in a life time?
???