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Scientists discover essential step in recharging the eye's light-sensing retina (Cysteine & Vitamin A)
Medical Xpress / National Institutes of Health / Life Science Alliance ^ | Oct. 26, 2022 | Sheetal Uppal et al

Posted on 10/27/2022 8:19:02 AM PDT by ConservativeMind

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To: spankalib
If that is so, why are there so many dead bunnies on the road?

Maybe what they possess in eyesight they lack in brain power.

21 posted on 10/27/2022 1:37:50 PM PDT by noiseman (The only thing necessary for the triumph of evil is for good men to do nothing.)
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To: spankalib

It’s not their eyes but their rodent brains that are faulty when it comes to evading traffic.


22 posted on 10/27/2022 1:40:37 PM PDT by hopespringseternal
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To: ckilmer

You said in post #17 you’ve been “taking 500mg daily.”

Is it 500 mg or 2,000 mg?


23 posted on 10/27/2022 1:42:25 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I had to discontinue glycine due to severe breakthrough heartburn. DRAT!!!😡 Found the comment of one other person reporting the same thing. Besides the presumed glutathione - related benefits, it did work as a sedative also, until I woke up from heartburn! Will be looking for another form which might not do this. Taking with / without food made no difference.


24 posted on 10/27/2022 1:46:05 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: steve86

What dose did you take and did you take the same amount of NAC?


25 posted on 10/27/2022 1:47:05 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I made a mistake.

I thought that my taurine was 500 mg pills.

Turns out they are 1000 mg pills.

I always take taurine at night as part of my evening stack. It serves as a sleep aid.

Some nights I take a second set of sleep aid supplements including taurine and glycine —and others.


26 posted on 10/27/2022 2:04:40 PM PDT by ckilmer (q)
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To: ConservativeMind

One gram or two grams at a time and approximately the same amount of NAC (1200 or 1800 mg). Still taking the NAC.


27 posted on 10/27/2022 2:13:42 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: steve86

Consider simply taking 500 - 600 mg of each, at a time.

Space them apart by a few hours for added doses.


28 posted on 10/27/2022 2:16:26 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Yes, I was going to try that but it will be hard to work up to an adequate amount per day.


29 posted on 10/27/2022 2:19:39 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: steve86

When your body doesn’t have a need for that much glutathione, it lets the glycine and NAC float around to do “other things.”

For you, some of those “other things” sound unhelpful.

Definitely, excess glycine can make people sleepy.

Since our cells can only convert so much glutathione at a time, you just need to tone it down a bit.


30 posted on 10/27/2022 2:20:01 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: steve86

An “adequate amount” for someone young may be “none at all.”

All this is doing is filling in for a process that becomes more broken as we age.

You may think you need “more,” but if your body tells you it can’t convert it all to glutathione, your body thinks it has enough. Glutathione lasts a few hours.

This is not a case where “more is better,” unless your body is in desperate need of it, then more cells can do more with the components.

Look into taurine for SOD help, but low dose that, too.

Only 80 year olds can effectively use a lot more at a time, and they need to dose it multiple times through the day.

What makes you think you need “more?”


31 posted on 10/27/2022 2:26:54 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

do NAC and vitamin a work independently to improve the eyes or do they work together to improve the eyes.


32 posted on 10/27/2022 3:09:01 PM PDT by ckilmer (q)
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To: ConservativeMind

Started taking Glutathione years ago.Helped with a lot of problems.

When granddaughter had gut problems she took it, helped her immensely.

I take Now brand 250 mg.

https://drhyman.com/blog/2010/05/19/glutathione-the-mother-of-all-antioxidants/


33 posted on 10/27/2022 3:22:47 PM PDT by sweetiepiezer (WINNING is not getting old!!! ❤️USA❤️)
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To: ConservativeMind
I'm not particularly young (67) and was going by the Lizzo, et.al. study protocols:

(GlyNAC) at three different daily doses for 2 weeks (low dose: 2.4 g, medium dose: 4.8 g, or high dose: 7.2 g/day, 1:1 ratio)

34 posted on 10/27/2022 4:00:44 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: steve86
Assuming a similar split dosage to prior March 2022 study, as the Lizzo study states they followed, they had half the total amount in the morning and the other half in the evening.

Nestle bought the patent rights to sell GlyNAC, and their retail dose is 1,200 mg of GlyNAC (600 mg of glycine and 600 mg of NAC a dose), twice a day, meeting the low daily tested amount of 2,400 mg of GlyNAC a day.

Knowing glutathione can last only a few hours, my wife and I broke this down to three times a day, 1,200 mg of GlyNAC each time, making what we take as 3,600 mg of GlyNAC a day (1,800 mg of glycine and 1,800 mg of NAC).

35 posted on 10/27/2022 6:46:23 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind
The glycine capsules I have are 1 gram each; wishing I had purchased a smaller capsule size.

From Lizzo:

A powder blend of N-acetylcysteine (NAC) and glycine was tested at three different daily doses: 2.4 g of actives (1.2 g NAC + 1.2 g glycine), 4.8 g of actives (2.4 g NAC + 2.4 g glycine), and 7.2 g of actives (3.6 g NAC + 3.6 g glycine) per day. Each dosage was split into two doses consumed in the morning and in the evening.

Only the middle and high doses achieved a statistically significant increase in glutathione, and that was only in older subjects who were low to begin with.

36 posted on 10/27/2022 7:45:02 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: steve86

The Lizzo study only tested GlyNAC for two weeks. Other studies have used it in humans for 24 weeks, and these older people incrementally got better the whole time.

If someone does not have a problem with making enough glycine or cysteine, additional GlyNAC is not going to help much.

Thankfully, it’s cheap and the amino acids have other duties to perform.


37 posted on 10/27/2022 8:02:53 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: steve86

I stand corrected. The young adults only had GlyNAC for two weeks, but the older adults did for 16 weeks. The older adults saw great benefit already at the 2 week mark, which no young adult got, but they were already young and healthy.

On the study from last year, the older adults took it 24 weeks and they did see some benefits last twelve weeks after the last dose, but other indicators went nearly back to normal.

Both of these show GlyNAC needs to be taken consistently to give older adults the young adult health advantage.


38 posted on 10/27/2022 9:19:22 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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