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Mouthwashes may suppress SARS-CoV-2 (Low concentration cetylpyridinium chloride)
Medical Xpress / Hokkaido University / Scientific Reports ^ | Oct. 6, 2022 | Ryo Takeda et al

Posted on 10/06/2022 2:52:01 PM PDT by ConservativeMind

SARS-CoV-2, the virus that causes COVID-19, is an airborne disease transmitted via aerosols, which are spread from the oral and nasal cavities—the mouth and the nose. In addition to the well-known division and spread of the virus in the cells of the respiratory tract, SARS-CoV-2 is also known to infect the cells of the lining of the mouth and the salivary glands.

Commercially available mouthwashes contain a number of antibiotic and antiviral components that act against microorganisms in the mouth. One of these, cetylpyridinium chloride (CPC), has been shown by a team of researchers led by Professor Kyoko Hida to reduce the viral load of SARS-CoV-2 in the mouth, primarily by disrupting the lipid membrane surrounding the virus. While there are other chemicals with similar effects, CPC has the advantage of being tasteless and odorless.

The researchers were interested in studying the effects of CPC in Japanese mouthwashes. Mouthwashes in Japan typically contain a fraction of the CPC compared to previously tested mouthwashes. They tested the effects of CPC on cell cultures that express trans-membrane protease serine 2 (TMPRSS2), which is required for SARS-CoV-2 entry into the cell.

They found that, within 10 minutes of application, 30–50 µg/mL of CPC inhibited the infectivity and capability for cell entry of SARS-CoV-2. Interestingly, commercially available mouthwashes that contain CPC performed better than CPC alone. They also showed that saliva did not alter the effects of CPC. Most significantly, they tested four variants of SARS-CoV-2—the original, alpha, beta and gamma variants—and showed that the effects of CPC were similar across all strains.

This study shows that low concentrations of CPC in commercial mouthwash suppress the infectivity of four variants of SARS-CoV-2. Future work will also focus on fully understanding the mechanism of effect, as lower concentrations of CPC do not disrupt lipid membranes.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: cetylpyridinium; chinavirusprevention; chinavirustreatment; covid; cpc; mouthwash
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To: ConservativeMind

Covid... Scam of the century and Covid Cultist still believe the BS.


21 posted on 10/06/2022 6:44:46 PM PDT by maddog55 (The only thing systemic in America is the left's hatred of it!)
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To: ConservativeInPA

If you never get tested, you’ll never get covid. Worked for me for over two years.


22 posted on 10/06/2022 6:47:52 PM PDT by maddog55 (The only thing systemic in America is the left's hatred of it!)
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To: God luvs America

Crest, Oral B and Colgate all make a mouthwash that works. I use at the recommendation of my dentist for oral health.


23 posted on 10/06/2022 7:01:03 PM PDT by redangus
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To: God luvs America

No, serious. Good for you.


24 posted on 10/06/2022 7:09:49 PM PDT by nwrep
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To: ConservativeMind

Crest Pro Health Clinical — it’s got cpc.


25 posted on 10/06/2022 7:48:56 PM PDT by Buttons12 ( )
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To: God luvs America

I am also “jab free”. So few had the common sense to avoid it


26 posted on 10/07/2022 12:02:46 AM PDT by albie
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