Those w/ chronic back problems, sciatica, numbness, etc. that partake (in one form or another) of the evil weed will tell you the truth - it helps. A lot.
I partook back in the 70s, but decided I didn’t want to live in a delusory reality.
One day I just quit, with no withdrawal symptoms. I suppose the lack of physical dependence is a huge advantage over opioids.
Urolithin a alleviates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells through SIRT1/PGC-1α pathway (Supplement addresses back disc issues)
https://freerepublic.com/focus/f-chat/4074750/posts
It's one of three small studies I found on such a benefit from Urolithin A.
Maybe, never tried that.
I lost 60 pounds fasting intermittently, and I’ll tell you what - something I didn’t even consider, however fat loss does more for sciatica, joint pain, etc than any pill.
Does it really help pain, or does it distract one from the pain by making one feel mellow and stoned?