Vanden Bossche's thesis, from his accompanying paper:
"As Omicron is highly infectious, individuals are now at risk of rapid reexposure to the virus. It follows that highly vaccinated populations are now placing more and more immune pressure on the infection-enhancing site within the S-NTD to prevent Omicron from causing systemic disease. I posit that this immune pressure is now at risk of driving natural selection of new SC-2 variants (‘Newco variants’) that will be endowed with one or more O-glycosylation sites that can shield the conserved NTD region comprising the non-neutralizing enhancing epitopes and thereby escape the disease-mitigating effect exerted by the enhancing anti-NTD Abs in vaccinees. Hence, natural selection of mutations enabling more extensive O-glycosylation of spike protein would not only make Newco variants fully resistant to all potentially neutralizing vaccine-induced Abs directed at spike protein (S), and thereby enable an even higher level of viral infectiousness, but also render these new immune escape variants more virulent for vaccinees. As site-specific O-glycosylation of S would abrogate Abmediated protection against severe disease in vaccinees, Ab-dependent enhancement of viral infectiousness (ADEI) would now directly translate into Ab-dependent enhancement of C-19 disease (ADED)."
This would ultimately result in a tsunami of hospitalizations and deaths in highly vaccinated populations whereas the unvaccinated would be better and better protected against the Newco variants thanks to their ‘enhanced’ (i.e., trained) innate immunity and because of reduced infectiousness and trans infectiousness of the virus in the upper and lower respiratory tract, respectively.
To translate:
Those who have submitted to being vaccinated, will keep getting infected over and over with new variants and risk a higher rate of hospitalization and/or death from the virus.
Those who did not get vaccinated will have a far better success rate in combating the virus, due to natural immune system kicking in and that immune system not having been corrupted by the "vaccines".
I think this is already occurring, to a degree. He predicts it will increase in size & scope.