Chip makers are pretty close to reaching the bottom. Since this technology is about to max out something needs to replace it. What that will be I can only guess. Nature has been making creatures that think for much longer. Perhaps something along those lines.
They're getting close to reaching the state of the possible with some aspects of chip making, but there are plenty of other areas that can be improved upon and many that have never been seriously pursued that will keep physicists, engineers, and mathematicians busy for many years.
They are reaching limits on two-dimensional structures. Three dimensional chips are the next frontier.