Bill Sardi wrote an article about vitamin C that talked about this
If you want to keep your body saturated all day long with vitamin C. Take 225mg C every two hours. More than this and it just washes out and is not utilized. Less than this and you will not be 100% saturated. By vitamin C I mean 225mg of sodium ascorbate powder or swallowing a 250mg capsule or tablet of vitamin C. Or alternate them during your awake hours.
By saturated, I mean at maximum vitamin c levels.
So if you are ill and think maximum vitamin C will help — Take 225 mg every two hours.
Thank you. I will look into this.
My dose is based upon Pauling.