There is all kinds of correlational evidence for several classes of anticholinergics — dismiss it if you will with the “not causation” quip, but I will no longer take first-generation antihistamines or other drugs such as antidepressants with anticholinergic characteristics. Take a later antihistamine instead such as cetirizine — a physically larger molecule that doesn’t usually pass the blood-brain barrier — and see if it works for the long-covid mitigation.
is there an OTC version for the kind you are willing to take?
Take a later antihistamine instead such as cetirizine — a physically larger molecule that doesn’t usually pass the blood-brain barrier — and see if it works for the long-covid mitigation.
I have no position on the issue, I was quoting two physicians (both of whom I regard as very knowledgeable) who have divergent opinions regarding Benadryl & dementia. I occasionally take it for its somnolent effects (not for long-covid), which later classes of antihistamines unfortunately have not had on me...although I have not tried Zyrtec specifically, so that may be worth a shot.