These are the two important paragraphs, as they detail how such large clots are formed in some Covid (or even vax induced as these clots are a function of the spike protein) victims:
But enough of this fear-mongering. Researchers have identified a set of already approved drugs that prevent spike-induced cell fusion and inhibit TMEM16F, a critical protein for syncytium formation. TMEM16F has the dual role of being a calcium-activated ion channel that regulates chloride secretion, as well as a lipid scramblase that relocates phosphatidylserine (PS) to the cell surface. This PS externalization is required for cell fusion in many systems, including spike-induced syncytia. Incidentally, scramblases also control the rate-limiting steps of the blood coagulation cascade, and may be the mechanism behind spike-induced thrombosis.
The blood coagulation pathways are a whole separate complex can of worms, but suffice it to say here that the primary trigger of coagulation induced by viral infections is the so-called extrinsic 'tenase.' Tenases are enzymes that process Factor X, or FX, (hence ten-ase), in the Tissue Factor (TF) activation pathway, which essentially act as the fuse for thrombus generation. The resulting complexes are assembled on externalized PS in the presence of calcium ions. TF is, in a sense, encrypted and so is unable to activate its downstream target factor FVIIa until it is de-encrypted by externalized PS.
PING
You may find this interesting.
P4L
I responded to the excerpt.
I cannot read the article.
I am familiar with Phys.org.
No need for your insults which show a bad faith as bad as you accuse me of.
I’ll read your post and respond.
“blood coagulation pathways are a whole separate complex can of worms”
You said it.
This is a hodgepodge of biochemical recitations that are not particularly coherent in making any point.
As you rightly state above, syncytial formation, that pretty much any virus can cause, has little if nothing to do with coagulation.
Activation of innate immune system triggers many effects including coagulation.
Single stranded RNA is an activator of this system and the vaccines are of course single stranded RNA.
If there is a real scientific article about what point is trying to make point me to it.