Weight loss reduces the risk of growths linked to colorectal cancer (For overweight people, only, a 46% lower risk of ‘polyps’)

Medical Xpress / Oxford University Press / JNCI Cancer Spectrum ^ | Feb. 1, 2022 | Shisi He et al

[ConservativeMind]

A new paper indicates that overweight and obese people who lose weight may reduce their chances of later developing colorectal adenoma—a type of benign growth or polyp in the colon or rectum that could lead to colorectal cancer. Colorectal cancer is the third most common type of cancer and the third leading cause of death from cancer among men and women in the United States.

Obesity is a known risk factor for colorectal adenoma and colorectal cancer.

Doctors recommend weight loss for overweight and obese people commonly. Although weight loss is thought to have some beneficial health effects, whether losing weight can reduce the chance of developing colorectal adenoma has been an open question.

The investigators found that, compared to stable weight, weight loss in adulthood (defined as loss greater than or equal to 1.1 pounds per 5 years) was associated with a 46% reduced risk for colorectal adenoma. This was particularly true among adults who were initially overweight or obese. The investigators also reported that weight gain in adulthood was associated with an increased chance of adenoma, particularly for weight gain greater than 6.6 pounds over 5 years. The researchers believe that the findings suggest the importance of healthy weight maintenance throughout adulthood in preventing colorectal adenoma. Additionally, adults who are overweight or obese may be able to reduce their risk for developing colorectal adenoma by losing weight.

"Our findings suggest that avoiding weight gain in adulthood may help lower someone's chance of developing a pre-cancerous growth called colorectal adenoma, which may in turn reduce the risk of developing colorectal cancer," said the study's senior author, Kathryn Hughes Barry. "Based on our findings, we would not recommend weight loss for all adults. But the results suggest that overweight and obese adults may benefit from weight loss."

[ConservativeMind]

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[DannyTN]

Rectum? Dang near killed ‘em!

[EEGator]

Be it any disease, the best thing to do is don’t be fat.
Eat “Paleo”, lift weights/sprint/do Yoga, and get good sleep.
I also strongly recommend meditation.

[ProtectOurFreedom]

Adult weight loss is “defined as greater than or equal to 1.1 pounds per 5 years.”

I track my weight closely and can swing that much in a week!

My Excel spreadsheet started January 3, 2002 — wow, 20 years of weight data. I hadn’t looked at the start date in ages. I was 180 back then and 187 today, so not heading in the right long-term direction (but I am down 10 pounds from last July). I’ve averaged 187 over those 20 years so I’m right at my average today.

My goal is to get back to 170...and to stop yo-yo-ing.

[DEPcom]

“Eat “Paleo””

I have been on a Paleo diet since last Sept, lost 20 pounds. I feel 100% better and looking forward to hiking this Springtime.

[EEGator]

That’s great, it really helps and is simple to follow.

[yefragetuwrabrumuy]

It’s very important to distinguish between Colon Polyps vs. Diverticulitis. 1% of colon polyps may turn into cancer.

The risk of having colorectal cancer after an episode of acute diverticulitis is 44-fold higher than that of an age- and gender-adjusted reference population. Despite lower among patients with uncomplicated episode, the risk of colorectal cancer remains 40-fold higher in that subpopulation than that in the reference population.