Study: Nearly 1 in 7 COVID patients in ICU experienced severe bleeding when given full-dose blood thinners (Better to give just “higher than normal” dose)

Medical Xpress / University at Buffalo / ^ | Jan. 28, 2022 | Marcene Robinson / Maya R. Chilbert et al

[ConservativeMind]

Patients with COVID-19 in the intensive care unit (ICU) prescribed full-dose blood thinners are significantly more likely to experience heavy bleeding than patients prescribed a smaller yet equally effective dose.

The research, which compared the safety and effectiveness of blood clot treatment strategies for more than 150 critically ill COVID-19 patients at two hospitals, found that almost all patients who experienced significant bleeding were mechanically ventilated and receiving full-dose anticoagulants (blood thinners).

The results may inform treatment guidelines for blood clots in hospitalized COVID-19 patients, who are at an increased risk for both blood clots and severe bleeding. Previous reports have found that 17% of hospitalized COVID-19 patients experience blood clots, says Maya Chilbert, PharmD.

"A wide variety of practice exists when it comes to approaching blood clots in hospitalized patients with COVID-19, and there is little data to suggest improved outcomes using one strategy versus another," says Chilbert. "Caution should be used in mechanically ventilated patients with COVID-19 when selecting a regimen to treat blood clots, and the decision to use full-dose blood thinners should be based on a compelling indication rather than lab markers alone."

The study analyzed the outcome of blood clot treatments and the rate of bleeding events for more than 150 patients with COVID-19 who received either of two blood thinner regimens: a full-dose based on patient levels of D-dimer (a protein present in the blood after a blood clot dissolves), and the other a smaller but higher-than-standard dosage.

Nearly 14% of patients who received full-dose blood thinners experienced a significant bleeding event, compared to only 3% of patients who received a higher-than-standard dosage. All patients who experienced bleeding events were mechanically ventilated. No difference was reported in the regimens' effectiveness at treating blood clots.

[ConservativeMind]

Please provide this to a doctor expecting to treat a loved one in the ICU.

[ConservativeMind]

The “Take Charge Of Your Health” Ping List

This potentially high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to implement for your benefit.

Please email or private message me if you want on or off of this list.

[RushIsMyTeddyBear]

Bkmrk

[Deaf Smith]

Missing from the story...

Was the need for blood thinners to prevent blood clots due to medical history of being "vaccineted" and "boosted"?

[datura]

I had the J&J just over a month ago. Lots of muscle pains these days - I’m getting a d-dimer test this week.

[logi_cal869]

Noticed that, too.

Curiously, the study is well-protected, hiding behind published media templates, the OP being one of them, and behind a paywall.

Here’s the study’s abstract:

https://journals.sagepub.com/doi/pdf/10.1177/00185787211066456

[ProtectOurFreedom]

“Regimen A” vs “Regimen B”

$42 required to reveal the true identity.

[the_daug]

Blood thinners and steroids is what I was given at the hospital. Blood still seeps from the sinus four moths on and the blood does not look like the blood of a dry sinus.

[zeestephen]

These blood clot studies need a control group that starts taking one low dose aspirin every six hours after Covid symptoms first appear.

I bet you would knock out 75% of the clot related issues with no ICU and no hyper-expensive drugs.

[Tilted Irish Kilt]

Maybe we should bring back the Neolithic medication treatment and usage of " leeches".

[mewzilla]

Wonder how many of these patients were denied early treatment with something efficacious...