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Increasing incidence of early-onset colorectal precancerous lesions in patients under age 50
Medical Xpress / The Mount Sinai Hospital / Gastroenterology ^ | Jan. 11, 2022 | Steven H. Itzkowitz, MD, FACP

Posted on 01/11/2022 12:02:15 PM PST by ConservativeMind

Researchers describe a troubling increase in early-onset colorectal cancer and precancerous polyps, based on a large, nationally representative study of patients under age 50 who underwent colonoscopy. It was the first large-scale study to look at precancerous polyps in this age group.

"We have known for many years that rates of colorectal cancer are rising in individuals younger than 50, prompting several medical organizations to recommend lowering the screening age from 50 to 45. What has been missing until now is confirmatory data of the prevalence of precancerous polyps in younger individuals. Because precancerous lesions are not reportable to regional or national health agencies, we have not had this degree of information to guide our recommendations. Our study provides an important piece of the puzzle and supports the recommendation changing the screening age to 45," says lead author Steven H. Itzkowitz, MD. "Our findings also suggest that messaging aimed at young individuals should begin in the years leading up to this new screening age. We know that most patients do not call their doctors on their 50th birthday to schedule a colonoscopy, so we will need to be diligent to reach this much younger cohort before they turn 45," says Dr. Itzkowitz.

Increasing age, being male and white, having a family history of colorectal cancer, and having had colonoscopies for reasons of bleeding or screening, were all associated with higher odds of advanced premalignant lesions (APLs) and colorectal cancer. Among patients aged 45-49, 32 percent had neoplasia (precancerous or cancerous lesions considered forerunners to colorectal cancer). Nearly 8 percent had APLs, and 0.58 percent had colorectal cancer.

Early-onset colorectal cancer accounts for approximately 12 percent of all colorectal cancer cases, with incidence increasing by 2.2 percent annually from 2012-2016, and mortality increasing by 1.3 percent per year from 2008-2017.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: colonoscopy; colorectalcancer; polyps
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To: steve86

All kidding aside…do the crap on a card thing. Most of the time that would get the job done.


61 posted on 01/11/2022 2:41:55 PM PST by Vermont Lt
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To: mmichaels1970

That prep, unfortunately doesn’t work for me. I have to have the Dulcolax tablets, Gatorade, and one or two jugs of the Golitly solution either one or two days ahead of time. And of course, fasting one or two days ahead. My wife says it’s because I’m so “full of it”.🤪


62 posted on 01/11/2022 2:42:05 PM PST by telescope115 (Proud member of the ANTIFAuci movement. )
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To: mass55th

I have Ulcerative Colitis, they removed a pre-cancerous polyp out of me two years ago. I was diagnosed in 1994, and I’m 67 now. I’ll be getting them for a while longer….


63 posted on 01/11/2022 2:47:20 PM PST by telescope115 (Proud member of the ANTIFAuci movement. )
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To: Vermont Lt

No kidding here. I refuse the fecal DNA test because they just refer for colonoscopy afterward anyway.


64 posted on 01/11/2022 3:12:17 PM PST by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: ConservativeMind

It takes longer without sedation. My first colonoscopy was sans sedation because I arrived alone—no driver assistance (wife on travel). It was fine, but occasional “cramp” feeling, which was uncomfortable, and introducing air causes cramps as well.


65 posted on 01/11/2022 3:20:53 PM PST by SgtHooper (If you remember the 60's, YOU WEREN'T THERE!!)
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To: Captainpaintball

Did the doc tell him to “bark like a dog! Bad boy! Bad boy!”


66 posted on 01/11/2022 3:26:02 PM PST by SgtHooper (If you remember the 60's, YOU WEREN'T THERE!!)
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To: telescope115
"I have Ulcerative Colitis, they removed a pre-cancerous polyp out of me two years ago. I was diagnosed in 1994, and I’m 67 now. I’ll be getting them for a while longer…."

Good luck to you. I hope those polyps are a thing of the past.

I was diagnosed with diverticulitis years ago, and followed the doctors warnings of what not to eat. I even excluded seeds although he hadn't specifically mentioned them. Despite restricting corn, popcorn, nuts, and seeds, I ended up with a perforated bowel back in 2010. I had to have a temporary colostomy for three months. Then they did the reversal. The remaining two abdominal surgeries I had, was to repair an incisional hernia where the colostomy stoma was, and to have my gall bladder removed. Because of the previous 3 surgeries, they couldn't do it laparoscopically, and had to open me up. Regardless, I was home the next day, and have never had a problem since. I can eat greasy food without issue. I'd read that a lot of people who have their gall bladder removed, get diarrhea, even after eating a burger.

67 posted on 01/11/2022 3:33:55 PM PST by mass55th ("Courage is being scared to death, but saddling up anyway." ~~ John Wayne )
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To: ConservativeMind

After reading more about this, you MUST be sure that using the CG approach, does not cancel out normally covered colonoscopy procedure. I see some peeps were billed 1900-2000$ out of pocket.


68 posted on 01/11/2022 3:36:54 PM PST by SgtHooper (If you remember the 60's, YOU WEREN'T THERE!!)
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To: ConservativeMind

The sedation I received was good. I was apparently slightly conscious because they had to twist and turn me because my bowels have weird twists and turns in them. As I was awakening, the nurse asked me if I remembered it and I said no. Coming out of anesthesia was relatively quick and easy. It simply blocks your memory.

Anesthesia today is very different from years ago. You can be sitting up and talking in an hour or less without massive hangover.

I have to have stent surgeries...all to often. My first one was great. Following surgeries were done by a different doctor and he tends to go as light as he can with anesthesia, therefore the surgeries are absolute traumatic torture. It’s horrible. And then he doesn’t want to give pain meds post surgically.

I’m moving to a different state, therefore I will be seeing different doctors...thank God.

Don’t complain if your procedures are painless. I tend to be cautious about chemicals, too, but some simply are necessary at times.


69 posted on 01/11/2022 6:30:16 PM PST by PrairieLady2
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To: ConservativeMind

The sedation I received was good. I was apparently slightly conscious because they had to twist and turn me because my bowels have weird twists and turns in them. As I was awakening, the nurse asked me if I remembered it and I said no. Coming out of anesthesia was relatively quick and easy. It simply blocks your memory.

Anesthesia today is very different from years ago. You can be sitting up and talking in an hour or less without massive hangover.

I have to have stent surgeries...all to often. My first one was great. Following surgeries were done by a different doctor and he tends to go as light as he can with anesthesia, therefore the surgeries are absolute traumatic torture. It’s horrible. And then he doesn’t want to give pain meds post surgically.

I’m moving to a different state, therefore I will be seeing different doctors...thank God.

Don’t complain if your procedures are painless. I tend to be cautious about chemicals, too, but some simply are necessary at times.


70 posted on 01/11/2022 6:30:19 PM PST by PrairieLady2
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To: ConservativeMind

The sedation I received was good. I was apparently slightly conscious because they had to twist and turn me because my bowels have weird twists and turns in them. As I was awakening, the nurse asked me if I remembered it and I said no. Coming out of anesthesia was relatively quick and easy. It simply blocks your memory.

Anesthesia today is very different from years ago. You can be sitting up and talking in an hour or less without massive hangover.

I have to have stent surgeries...all to often. My first one was great. Following surgeries were done by a different doctor and he tends to go as light as he can with anesthesia, therefore the surgeries are absolute traumatic torture. It’s horrible. And then he doesn’t want to give pain meds post surgically.

I’m moving to a different state, therefore I will be seeing different doctors...thank God.

Don’t complain if your procedures are painless. I tend to be cautious about chemicals, too, but some simply are necessary at times.


71 posted on 01/11/2022 6:30:21 PM PST by PrairieLady2
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To: ConservativeMind

The sedation I received was good. I was apparently slightly conscious because they had to twist and turn me because my bowels have weird twists and turns in them. As I was awakening, the nurse asked me if I remembered it and I said no. Coming out of anesthesia was relatively quick and easy. It simply blocks your memory.

Anesthesia today is very different from years ago. You can be sitting up and talking in an hour or less without massive hangover.

I have to have stent surgeries...all to often. My first one was great. Following surgeries were done by a different doctor and he tends to go as light as he can with anesthesia, therefore the surgeries are absolute traumatic torture. It’s horrible. And then he doesn’t want to give pain meds post surgically.

I’m moving to a different state, therefore I will be seeing different doctors...thank God.

Don’t complain if your procedures are painless. I tend to be cautious about chemicals, too, but some simply are necessary at times.


72 posted on 01/11/2022 6:30:26 PM PST by PrairieLady2
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To: ConservativeMind

The sedation I received was good. I was apparently slightly conscious because they had to twist and turn me because my bowels have weird twists and turns in them. As I was awakening, the nurse asked me if I remembered it and I said no. Coming out of anesthesia was relatively quick and easy. It simply blocks your memory.

Anesthesia today is very different from years ago. You can be sitting up and talking in an hour or less without massive hangover.

I have to have stent surgeries...all to often. My first one was great. Following surgeries were done by a different doctor and he tends to go as light as he can with anesthesia, therefore the surgeries are absolute traumatic torture. It’s horrible. And then he doesn’t want to give pain meds post surgically.

I’m moving to a different state, therefore I will be seeing different doctors...thank God.

Don’t complain if your procedures are painless. I tend to be cautious about chemicals, too, but some simply are necessary at times.


73 posted on 01/11/2022 6:30:29 PM PST by PrairieLady2
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To: Valpal1

I didn’t even think about that. Excellent point.


74 posted on 01/11/2022 7:39:24 PM PST by refreshed (But we preach Christ crucified... 1 Corinthians 1:23)
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To: 4Liberty

Without a doubt.


75 posted on 01/11/2022 7:40:26 PM PST by refreshed (But we preach Christ crucified... 1 Corinthians 1:23)
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To: C210N

Oh my.


76 posted on 01/12/2022 3:18:04 PM PST by CatHerd (And we are are on earth a little space, That we may learn to bear the beams of love - William Blake)
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