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To: CatHerd

I thought autoimmune diseases like rheumatoid arthritis, lupus, Hashimoto’s, etc are because the immune system is overactive - targeting bodily systems, not underactive.

Am I misguided?


9 posted on 12/29/2021 3:53:09 PM PST by jacquej ("You cannot have a conservative government with a liberal culture." (Mark Steyn))
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To: jacquej

It’s probably an indirect correlation, caused by the immunosuppressant drugs prescribed for arthritis rather than the arthritis itself. Same for the transplant recipients, as they are on even stronger immunosuppressants.


15 posted on 12/29/2021 4:13:45 PM PST by ETCM
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To: jacquej

Autoimmune diseases are suppressed by down regulating immune system by different meds...that is why they have poor immune response. Transplant patient have medicine induced immunosuppression also. Plus specific autoimmune diseases attack certain tissues....not necessarily infectious agents.


25 posted on 12/29/2021 4:43:07 PM PST by Getready (Wisdom is more valuable than gold and diamonds, and harder to find.)
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To: jacquej

You already got good answers from ETCM and Getready here.

HIV attacks and destroys the infection-fighting CD4 cells of the immune system, which makes it harder for the body to fight off diseases.

Patients suffering from autoimmune diseases, such as rheumatoid arthritis and lupus, take drugs to tamp down their overactive immune systems.

Okay, found this in case it helps explain:

https://www.pennmedicine.org/updates/blogs/health-and-wellness/2020/may/what-it-means-to-be-immunocompromised


29 posted on 12/29/2021 6:30:47 PM PST by CatHerd (And we are are on earth a little space, That we may learn to bear the beams of love - William Blake)
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