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Popular blood thinners may lead to brain bleeding after head injury (Use newer blood thinning drugs and no aspirin)
Medical XPress / Radiological Society of North America ^ | Nov. 30, 2021 | Warren Chang, M.D., et al

Posted on 12/02/2021 7:32:23 AM PST by ConservativeMind

A three-year study found that the risk of delayed intracranial hemorrhage and death following head trauma was significantly higher for adults taking older blood thinning medications including clopidogrel (Plavix) and warfarin (Coumadin), according to research. Taking aspirin concurrently with any blood thinner may increase the risk of delayed hemorrhage.

Intracranial hemorrhage occurs when blood vessels within the brain rupture, releasing blood into the brain tissue. In a delayed traumatic intracranial hemorrhage, bleeding in the brain occurs after the initial trauma, usually within 48 hours, after an initial negative head CT.

High blood pressure, head injury and the use of blood thinners are known causes of intracranial hemorrhage.

Adults taking blood thinners who suffer head trauma typically undergo CT imaging of the brain. However, the standard of care beyond initial imaging is not well defined.

"Different hospital networks have different strategies for repeat imaging of these patients," Dr. Chang said.

Within the study group, 576 patients were taking one of the newer blood thinners, such as apixiban (Eliquis), rivaroxaban (Xarelto) and dabigatran (Pradaxa), and 470 patients were taking warfarin, clopidogrel or another older medication.

All deaths in the study group were among patients in the warfarin/clopidogrel/older blood thinner group.

Among the total study group, 345 patients were taking both blood thinners and aspirin. Of the 20 patients who suffered a delayed hemorrhage, 15 were taking an older type of blood thinner, and nine of the 15 were also taking aspirin.

"The rate of delayed hemorrhage was higher in patients taking older blood thinners compared to novel drugs, and significantly higher in patients taking aspirin in addition to the older medications," Dr. Chang said.

Among the five patients taking novel blood thinners who experienced a delayed hemorrhage, four were also taking aspirin.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
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To: Utah Binger
Having TAVR doesn't require you to have long term anticoagulation with drugs like Eliquis or Xarelto. Some physicians will do this for a short period after TAVR, but it's not required long-term - unless you have something else going on, like atrial fibrillation.
21 posted on 12/02/2021 8:16:37 AM PST by neverevergiveup
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To: digger48

I have been on Warfarin for the last 31 years due to an artificial heart valve and stent.
No problems so far but I do get my blood checked closely as my INR jumps from high to low all the time.


22 posted on 12/02/2021 8:18:08 AM PST by Ruy Dias de Bivar (OUT of Facebook Jail! But for how long?)
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To: webheart
That is a cheap internet ad headline.

That was my thoughts as well.

23 posted on 12/02/2021 8:19:52 AM PST by Utah Binger (Utah: Where the world comes to see America)
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To: neverevergiveup

Must be the afib or Heart flutter. I went off Eliquis full strength last year and had a small stroke.


24 posted on 12/02/2021 8:25:09 AM PST by Utah Binger (Utah: Where the world comes to see America)
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To: ConservativeMind

It’s what led to my dad’s death - had been on coumadin for years, hit his head in a fall, had undiagnosed brain bleed, fell three weeks later, found old bleed and new bleed and things went downhill from there.


25 posted on 12/02/2021 8:25:28 AM PST by jagusafr ( )
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To: monkeyshine

What makes you think I was jesting?
I think that is really what the study meant. “We can’t make money off our old drugs because they’re available as generics, so stop using them and buy our new drugs.”
I am particularly amused by the new studies telling us that aspirin is useless or bad for cardiovascular issues.


26 posted on 12/02/2021 8:26:05 AM PST by Little Ray (Civilization runs on a narrow margin. What sustains it is not magic, but hard work. )
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To: sport

I was on full dose aspirin for clots from the clot shot. I bumped my hand and bled through a vein. I put myself on low dose. Somewhere along the line I will reduce that.


27 posted on 12/02/2021 8:30:38 AM PST by Cold Heart
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To: sport

We’re not allowed to use the worm poison Ivermectin, but doctors will gladly give us rat poison.


28 posted on 12/02/2021 8:34:40 AM PST by ryderann
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To: ConservativeMind

“One benefit of the newer blood thinners is the ability to eat higher Vitamin K veggies”

So, if I use a newer blood thinner I can eat Kale for that wonderful dirt flavor I crave, and yummy Brussell Sprouts again! Yea! /s


29 posted on 12/02/2021 9:05:23 AM PST by DesertRhino (Dogs are called man's best friend. Moslems hate dogs. Add it up....)
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To: Mr Rogers

I agree.


30 posted on 12/02/2021 9:29:45 AM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

garbage study/paper: Plavix is an anti-platelet medication and the others are anti-coagulants. Anti-platelets inhibit clotting in the arteries and anti-coagulants inhibit clotting in veins, because arteries and veins have entirely different clotting mechanisms, and you cannot substitute one class of medications for the other, and to conflate the two classes of medications as “blood thinners” is childish nonsense.


31 posted on 12/02/2021 9:33:40 AM PST by catnipman (Cat Nipman: Vote Republican in 2012 and only be called racist one more time!)
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To: webheart

Good perspective.

I’m on eliquis and 1 baby aspirin to prevent blood clots and strokes. I’m doing fine.


32 posted on 12/02/2021 9:36:37 AM PST by aquila48 (Do not let them make you "care" ! Guilting you is how they control you. )
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To: rlmorel

Wonder why aspirin is suddenly the new deadly drug? Here ya go.

https://journals.lww.com/anesthesia-analgesia/fulltext/2021/04000/aspirin_use_is_associated_with_decreased.2.aspx


33 posted on 12/02/2021 9:37:49 AM PST by DesertRhino (Dogs are called man's best friend. Moslems hate dogs. Add it up....)
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To: kaktuskid

I took Xarelto then the doctor switched me to Eliquis but I was told not to take any Ibuprofen....nothing was said about Aspirin and I’ve stayed away from that forever anyway because of the damage it can do to a stomach. Now I take Tylenol if I have a headache. I always thought it was pretty ineffective before this but it seems to be ok.

There is a blood thinner with ZERO cost (Jantoven) and I did take that for awhile but it required getting the weekly blood test. I dislike all of it - it may be effective at avoiding strokes but the bleeding under the skin if your arms or hands even come close to hitting a door or wall is really annoying. I look like I’ve been beaten up.


34 posted on 12/02/2021 9:46:52 AM PST by Thank You Rush
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To: Utah Binger

And I just posted that bleeding under the skin is annoying. I’m sorry for not considering that is a minor annoyance compared to what you and others are going through. I wish you the best and take care.


35 posted on 12/02/2021 9:51:06 AM PST by Thank You Rush
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To: kaktuskid

“”grapefruit””

Is that true? I eat grapefruit - am on Eliquis - but I never heard that before.


36 posted on 12/02/2021 10:00:59 AM PST by Thank You Rush
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To: Thank You Rush
And I just posted that bleeding under the skin is annoying.

I appreciate that. Bleeding everywhere from a small bump gets very annoying. But you know it goes with the territory.

37 posted on 12/02/2021 10:01:02 AM PST by Utah Binger (Utah: Where the world comes to see America)
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To: sport

Had a horse trainer friend die about 6 mo ago, colt threw his head banged against a board on the stall, bled inside his skull and died.


38 posted on 12/02/2021 10:04:25 AM PST by allwrong57
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To: Utah Binger

“”But you know it goes with the territory.””

I do now. I didn’t know it and my cardiologist told me he didn’t think the Eliquis had anything to do with what he could see on my arms. I have COPD and take inhaled medications and the pulmonologist said it doesn’t come from those. It’s like talking to a bureaucrat and not getting a straight answer.

I had no idea the bruising was anything BUT bruising until I saw blood on the console in the car and it was coming from my elbow which I had hit on something and the “bruise” had broken open. I knew we were supposed to watch for “bleeding” but I did not know the bruises actually contained BLOOD...

I’ve kept my distance from the medical profession all my life (up until the COPD diagnosis), having been raised that way but I guess if I hadn’t been, I would today begin to doubt everything I’ve heard. Fauci would have me convinced my parents were right!!


39 posted on 12/02/2021 10:12:32 AM PST by Thank You Rush
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To: TBall

In Germany you cannot buy aspirin without going to a pharmacy. Can’t get it at the grocery store.


40 posted on 12/02/2021 10:14:14 AM PST by DesertRhino (Dogs are called man's best friend. Moslems hate dogs. Add it up....)
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