Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019

journals.lww.com ^ | Oct 21, 2020 | Jonathan H. Chow, Ashish K. Khanna, Shravan Kethireddy, et al

[ransomnote]

[H/T chuck allen]

Authors: Chow, Jonathan H. MD^*; Khanna, Ashish K. MD, FCCP, FCCM^†,‡; Kethireddy, Shravan MD^§; Yamane, David MD^∥; Levine, Andrea MD^¶; Jackson, Amanda M. MD^#; McCurdy, Michael T. MD^¶; Tabatabai, Ali MD^¶,**; Kumar, Gagan MD^§; Park, Paul MD^††; Benjenk, Ivy RN, MPH^*; Menaker, Jay MD; Ahmed, Nayab MD^§§; Glidewell, Evan MD^∥∥; Presutto, Elizabeth MD^††; Cain, Shannon MD^¶¶; Haridasa, Naeha BS^*; Field, Wesley MD^§§; Fowler, Jacob G. BS^∥∥; Trinh, Duy MD^††; Johnson, Kathleen N. BS^∥∥; Kaur, Aman DO^§§; Lee, Amanda BS^††; Sebastian, Kyle MD^∥∥; Ulrich, Allison MD^††; Peña, Salvador MD, PhD^∥∥; Carpenter, Ross MD^††; Sudhakar, Shruti MD^††; Uppal, Pushpinder MD^††; Fedeles, Benjamin T. MD, Capt, USAF, MC^††; Sachs, Aaron MD^††; Dahbour, Layth MD^††; Teeter, William MD^**,##; Tanaka, Kenichi MD^‡‡‡; Galvagno, Samuel M. DO, PhD^**; Herr, Daniel L. MD^**; Scalea, Thomas M. MD^**,‡‡; Mazzeffi, Michael A. MD, MPH^***Author Information

Anesthesia & Analgesia: April 2021 - Volume 132 - Issue 4 - p 930-941

doi: 10.1213/ANE.0000000000005292

 

EXCERPTS ONLY. DETAILS OF STUDY AT LINK. 

Excerpt: "In summary, our analysis suggests that aspirin use may have beneficial effects in patients with COVID-19. Mechanistically, these findings are plausible given aspirin’s irreversible antiplatelet effect and the frequent hypercoagulability observed in COVID-19 patients. The results of our study are intriguing, especially because aspirin has been thoroughly studied in chronic cardiovascular disease, has a well-described safety profile, and is readily available throughout the world. The preliminary, hypothesis-generating nature of our study provides the basis for a larger study, which will be needed to confirm our findings and assess the extent to which the relationships observed in our study are causal. Until a randomized controlled trial of aspirin is performed, it is imperative to exercise cautious optimism and deliberately balance aspirin’s known risks against its potential benefits in patients afflicted by COVID-19."

 

Aspirin Use Is Associated With Decreased Mechanical Ventilat... : Anesthesia & Analgesia (lww.com)

 

[rolling_stone]

there have been studies about von Willebrand factr and covid 19
below is one which concluded higher vwf was related with worse outcomes with covid19

https://pubmed.ncbi.nlm.nih.gov/33449299/

[GOPJ]

Aspirin’s one of the few true wonder drugs.

If it has been discovered years later than it was, we’d be paying a hundred dollars a pill and needing a prescription to get it.

[MachIV]

Thanks. I asked my doc about K2 not long ago and he advised against that. Having said that I will definitely up the anti on Brussel sprouts.

[saintgermaine]

Did you ask him why he is against K-2?

[BiteYourSelf]

Not for recommended for those with kidney disease.

[bray]

Looks like it works better than the vax.