Posted on 09/18/2021 9:39:28 AM PDT by Jan_Sobieski
[…]
Conclusion
ADE has been observed in SARS, MERS and other human respiratory virus infections including RSV and measles, which suggests a real risk of ADE for SARS-CoV-2 vaccines and antibody-based interventions. However, clinical data has not yet fully established a role for ADE in human COVID-19 pathology. Steps to reduce the risks of ADE from immunotherapies include the induction or delivery of high doses of potent neutralizing antibodies, rather than lower concentrations of non-neutralizing antibodies that would be more likely to cause ADE.
Going forwards, it will be crucial to evaluate animal and clinical datasets for signs of ADE, and to balance ADE-related safety risks against intervention efficacy if clinical ADE is observed. Ongoing animal and human clinical studies will provide important insights into the mechanisms of ADE in COVID-19. Such evidence is sorely needed to ensure product safety in the large-scale medical interventions that are likely required to reduce the global burden of COVID-19…
(Excerpt) Read more at nature.com ...
Every previous study up to January, 2021 warned of it…
19-ADE-4
Dr. Robert W. Malone warned of this long ago. And he was correct.
Are the monoclonal antibodies treatments high level, and thus would not elicit ADE responses?
The agency of ADE in Covid9 infection seems circumstantially correlated by so many Covid19 vaccinated persons getting a Covid19 infection far sooner than any study indicated their vaccination derived immunity might have passed.
It appears so many “fully vaccinated” persons are both getting a Covid19 infections and the same who are needing hospitalization that great effort MUST be put into the research to determine how much of a role that ADE is playing in that.
I don’t know. Don’t think it is based on genetic engineering.
It seems the demand is strong for it. It must work.
Two weeks till ADE is the reason we have to jab everyone
Dr. Robert W. Malone warned of this long ago. And he was correct.
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A dark fall and winter lie ahead for the vaxed, where immune systems have been wrecked with the spike protein. Even coming late to the dance with HCQ and ivermectin cocktail treatments may not work for the immune-compromised.
To which GovCo darksiders say: “If, at first, you don’t succeed, try, try again.”
Testing and recent history suggest that skeptics live longer than volunteer test lemmings do.
A closed herd vaccinated to 100% do not have breakthroughs because they are not exposed.
An open herd vaccinated to 50^ with frequent introductions of unvaccinated animals will be a consistently sick herd
Historically, herd immunity was from being exposed to a virus and gaining “natural immunity”. The addition of vaccines is a recent innovation
Historically, herds were protected by keeping closed herds = nobody in nobody out.
Hoof and mouth disease has been around for 50,000 years or more. Where’s the ‘natural’ immunity?
Dental decay in humans and animals has been around for 500,000 years. Where’s the natural immunity?
AIDS has been around for 40 years - any natural immunity yet?
How about cancer? lung disease? kidney disease?
what many breakthroughs?
unvaccinated who survive one infection have about 80% protection over reinfection; over 65 less than 50%. Unlike vaccinated reinfected, unvaccinated reinfected tend to have more severe disease the second time around. Similar to vacccinated immunity, ‘natural immunity’ fades over time and immunity to Wuhan version doesn’t mean immunity to Delta or other variants. Many vaccinated reinfected were captive audience nursing home residents repeatedly exposed to unvaccinated caregivers. Many unvaccinated reinfected were exposed by their own social patterns.
reinfection rate among unvaccinated last year was 5%, a rate 2.5x that of vaccinated elderly.
among Kentucky residents who were previously infected with SARS-CoV-2 in 2020, those who were unvaccinated against COVID-19 had significantly higher likelihood of reinfection during May and June 2021... a recent laboratory study found that sera collected from previously infected persons before they were vaccinated provided a relatively weaker, and in some cases absent, neutralization response to the B.1.351 (Beta) variant when compared with the original Wuhan-Hu-1 strain (1).
https://www.cdc.gov/mmwr/volumes/70/wr/mm7032e1.htm
from a qatar study - avg age 33 (blind test: swabs didn’t know what nose they were going up):
vaccinated pcr test at airport 0.8%
unvax prior inf pcr airport test 1%
unvax no prior pcr airport test 3.8%
https://jamanetwork.com/journals/jama/fullarticle/2781112
percentages percentages percentages
no matter how much less the vaccinated reinfections rate, compared to the not vaccinated reinfections, it is still higher than it ought to be, and ADE ought to be considered part of the reason
You are mixing/linking together some things - diseases - that have little in common including method of transmission.
A certain level of herd immunity was always acceptable for the seasonal flu, another set of viruses transmitted through the nose and mouth, so why is it not germane to Covid19?
“Natural immunity” is an immune system response acquired by the immune system meeting, challenging and eventually overcoming an infection. The immune system retains the immune system agents that mounted that successful defense for some time afterward, and varying in degree and longevity by the different immune system agents and varying by individual as well.
As a personal matter I never in my life had a serious flu illness and never had the flu vaccine. My immune system alone has been successful against the flu for these many decades of my life. Yes, that represents some degree of “natural immunity”.
But it can’t all be blamed on vaccinated - there is at the least, can we agree, a 50/50 kind of thing going on? Vaccinated and unvaccinated recovered both at about 80% good or better? (age dependent for both)
ADE is a non-issue right now since the goal is to eliminate the spread down to isolated outbreaks that can be managed, and, hopefully, we’ll have something besides monoclonals and vaccines on the shelf.
There are a few studies. One discussed the possibility of ADE as it has to do with the individual’s own interferon deficiencies. Another discusses the use of vaccines antibodies targeting the S protein but not recognizing the N gateway which is prone to creating autoantibodies and that future vaccines should target the I think it was LAIR pathway? Something like that.
Another, in response to the reinfection rate of previously infected and why they tended to have more serious reinfections (2 challenges to the immune system) than the mild reinfections of the double-vaccinated (3 challenges to the immune system) , was not the number of times a person was challenged, which ADE depends on. But that the ‘wild’ spike antibodies also didn’t recognize the N gateway and triggered even more autoantibodies when challenged with the delta version. Which led to a recommendation to either reengineer the vaccine to address both pathways, or to replace the ‘wild’ spike in the vaccines with the ‘delta’ spike’ and recommend ‘naturals’ get a one-shot booster. (which is what I thought they were supposed to be doing for the boosters anyway).
Only God knows the scope of the damage already done.
It is clear to me that the companies really don’t fully understand what they are playing with. If they do, then they are truly evil.
You forget your shooting a moving target because of the new strains coming on line. And they come on as a reaction to the vaccine. Dr. Malone explained this concept many months ago and said it was known among the virologists. The mRNA vaccine is narrow in targeting. Those un-vaxed who recover from the virus have a broader immunity and can handle the mutations.
I am getting Pfizer death jab #3 next week, so if I stop posting, you will know what happened.
Hee hee.
I wish you the best.
I’m holding tight here.
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