American Scientists Confirm Toxic Graphene Oxide, and More, in Covid Injections
Posted on 09/01/2021 11:26:19 AM PDT by Red Badger
More than a year after the start of the COVID-19 pandemic, several vaccines have been authorized thanks to unprecedented worldwide research efforts. These first-generation vaccines bring great hope and are a mainstay in fighting the virus. However, questions persist regarding the duration of the immune response or the need for a booster. Also, controlling the pandemic means vaccinating billions of people. Yet manufacturing sufficient doses to protect the entire world population represents a considerable challenge. That is why vaccine research is still ongoing in order to develop additional candidate vaccines and to continue to meet these various challenges.
Researchers from the Vaccine Research Institute (VRI) (Inserm/Université Paris-Est Créteil), CEA and Université Paris-Saclay are working on the development of a vaccine comprised of a monoclonal antibody that targets immune cells circulating throughout the body: dendritic cells. These cells play a key role in stimulating the immune system through their ability to induce a robust and long-lasting antibody and cellular response, as demonstrated by the team in other models of infection. The monoclonal antibody is fused to a SARS-CoV-2 protein, which stimulates the dendritic cells.
In addition, this dendritic cell targeting vaccine technology is currently in phase I of a clinical trial evaluating the safety and immunogenicity of a preventive HIV vaccine.
Restimulate the production of neutralizing antibodies In their study published in Nature Communications, the scientists began by studying the ability of their candidate vaccine to induce anti-COVID-19 “booster” responses in models using convalescent animals (having contracted SARS-CoV-2 six months earlier) .
They show that this vaccine is well tolerated and effective, inducing a strong increase in neutralizing antibodies. Faced with a new exposure to the virus, convalescent and vaccinated animals present an undetectable viral load or clear the virus in a shorter time (within three days) compared to unvaccinated convalescent animals or control animals free from any previous infection. A dose of this vaccine therefore provides better protection against reinfection than natural immunity. In addition, the vaccinated animals were protected from lung complications following infection.
Finally, the researchers have already adapted the candidate vaccine so that it is effective against the new variants identified in recent months. In the laboratory, the antibodies induced by the vaccine are capable of neutralizing very effectively the alpha variant (B.1.1.7) and also of neutralizing significantly the beta variant (B.1.351). Thus, the vaccine developed from the initial strain circulating in early 2020 is capable of inducing an antibody response that also neutralizes the new variants tested.
In conclusion, this study shows that a single administration of the candidate vaccine, with no adjuvant, restimulates the production of neutralizing antibodies capable of controlling the virus during reinfection. This provides better protection against reinfection than natural immunity. This vaccine could therefore supplement the arsenal of existing COVID vaccines. The results presented in this study suggest that it could be particularly useful for people recovering or already vaccinated whose immune response has started to decline, in order to strengthen their immunity. Due to the good knowledge of subunit vaccine safety, this vaccine could also be useful for vulnerable people or for immunizing children.
Clinical trials are planned for 2022 with convalescent patients or people who have already received a first-generation vaccine. They will also be carried out in individuals who have never been exposed to either vaccination or the virus.
Reference: “Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques”
by Romain Marlin, Veronique Godot, Sylvain Cardinaud, Mathilde Galhaut, Severin Coleon, Sandra Zurawski, Nathalie Dereuddre-Bosquet, Mariangela Cavarelli, Anne-Sophie Gallouët, Pauline Maisonnasse, Léa Dupaty, Craig Fenwick, Thibaut Naninck, Julien Lemaitre, Mario Gomez-Pacheco, Nidhal Kahlaoui, Vanessa Contreras, Francis Relouzat, Raphaël Ho Tsong Fang, Zhiqing Wang, Jerome Ellis III, Catherine Chapon, Mireille Centlivre, Aurelie Wiedemann, Christine Lacabaratz, Mathieu Surenaud, Inga Szurgot, Peter Liljeström, Delphine Planas, Timothée Bruel, Olivier Schwartz, Sylvie van der Werf, Giuseppe Pantaleo, Mélanie Prague, Rodolphe Thiébaut, Gerard Zurawski, Yves Lévy and Roger Le Grand, 1 September 2021, Nature Communications.
DOI: 10.1038/s41467-021-25382-0
Is this different from the mRNA vaccines?
“In addition, this dendritic cell targeting vaccine technology is currently in phase I of a clinical trial evaluating the safety and immunogenicity of a preventive HIV vaccine.”
Think that one just went down the tubes
So is that admitting that compulsion vax has no efficacy?
I have been reading that the China Virus has never been isolated. If that is true how can a proper vaccine be created to build antibodies to defeat the virus?
Researchers from the Vaccine Research Institute (VRI) (Inserm/Université Paris-Est Créteil), CEA and Université Paris-Saclay are working on the development of a vaccine comprised of a monoclonal antibody that targets immune cells circulating throughout the body: dendritic cells. These cells play a key role in stimulating the immune system through their ability to induce a robust and long-lasting antibody and cellular response, as demonstrated by the team in other models of infection. The monoclonal antibody is fused to a SARS-CoV-2 protein, which stimulates the dendritic cells.
Gotta feeling that isn't the truth. It was indeed isolated in a lab in Wuhan before it was released on the planet.
The world has been relying upon the data provided by China for the genetic sequencing of Covid.
What could possibly go wrong?
“Gotta feeling that isn’t the truth. It was indeed isolated in a lab in Wuhan before it was released on the planet.”
OK, but if that virus in China was bio engineered in some way as has also been suggested then what was released from the lab was not the original virus.
“I have been reading that the China Virus has never been isolated. If that is true how can a proper vaccine be created to build antibodies to defeat the virus?”
I know the source is Reuters, but FWIW:
https://www.reuters.com/article/factcheck-covid-rna-idUSL1N2LS27P
Thanks. I read the piece but to be honest I don’t have confidence in anything from Reuters.
SARS-CoV2 has been isolated and sequenced hundreds of thousands of times by numerous laboratories. Cultures are available to those with legitimate need and facilities. Hundreds of electron microscope images of the virus have been published. Wherever you are reading this, they are just spreading disinformation.
Yes.
For one thing, there is no RNA involved. This treatment is similar to a classic vaccine, in that a synthetic fragment of non-reproducing virus shell is introduced to the body and provokes a durable immune response.
Also, the target for this treatment is not the S1 protein on the virus. It is a different piece of a virus shell, presumably less toxic than the S1 protein. That idea needs very careful testing.
The S1 protein was originally chosen as the target for the mRNA treatments because the researchers believed it was stable and would avoid the Antibody Dependent Enhancement reaction. Oops. Looks like they were wrong on both counts, plus S1 is toxic by itself. It is complicated.
These things must be tested in small populations over a period of time before deployed to general distribution. We forget that at our peril.
Whatever escaped from the Wuhan lab has long since mutated into a much less lethal and more contagious form. That is what viruses do, especially those in the coronavirus family. Of course, what we see now is not the original virus.
It is still "close enough for Government work".
American Scientists Confirm Toxic Graphene Oxide, and More, in Covid Injections
Will it kill more or less jab-ees?
It seems to me simply changing one's lifestyle choices (homosexuality and IV drug use) can prevent HIV 100%...and at ZERO COST.
neutralizing very effectively the alpha variant (B.1.1.7) and also of neutralizing significantly the beta variant (B.1.351)
obsolete already? Pfitzer and Moderna were trailed against alpha (wild wuhan original recipe), too. And fell in efficacy against Delta. With DeltaPlus, Delta3, Lambda, Mu and Pango on the horizon, all improvements on Delta or the beta infectivity mechanisms, wouldn’t it make more sense to hold off and run trials against Delta first, like JJ, yes? Although I guess if they can cut into Pfitzer/Moderna’s market share, it’s a good thing.
can prevent HIV 100%
wrong
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