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The bitter truth of added sugar: What excessive fructose consumption can do to your body (Exhausts ATP/Causes Gout)
Medical XPress / Chinese Medical Journal ^ | Aug 30, 2021 | Ya-Nan Shi et al

Posted on 08/30/2021 9:54:54 PM PDT by ConservativeMind

In today's fast-paced world, the dependence on the widely available "fast" foods and beverages has risen. These foods are typically low in fiber and essential nutrients, and often consist of high amounts of added sugar. This shift in dietary trends, accompanied by a sedentary lifestyle, has been attributed to the rise in various metabolic disorders like diabetes, fatty liver disease, and heart disease. The concerning thing about sugar is that the more you eat it, the more you crave it—leading to a vicious cycle of excessive sugar consumption and poor health.

So what exactly is this added sugar and why is it so bad for us? To understand this, let us first understand the basics. Refined sugar (or "sucrose") is structurally composed of two simple forms of sugars called "glucose" and "fructose." Although these simple sugars are structurally similar to each other, they are metabolized via different pathways in the body. And while excessive fructose intake (even within "normal" ranges, to some extent) has been shown to be harmful for us, the underlying mechanisms behind fructose metabolism and their potential role in metabolic disorders have not been fully understood so far.

…Now when fructose enters circulation, its levels in the blood (albeit much lower than glucose) are kept at bay by the kidney and liver, both crucial metabolic hubs in our body. In these organs, fructose is redirected for glucose production, via a process called "gluconeogenesis." However, this reaction requires the breakdown of a molecule called "ATP" (the main source of energy in cells). Thus, an excessive intake of fructose can lead to ATP depletion in cells, which activates another pathway involved in uric acid metabolism—leading to an accumulation of uric acid in the blood and joints and increasing the risk of developing "gout" (a condition causing severe joint pain).

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS:
ATP is less an issue with younger or active people.

The issue is the same with sugar, high fructose corn sweetener, fruits, or fructose. There is a limit to how much fructose the body can properly detox before creating dysfunction.

1 posted on 08/30/2021 9:54:54 PM PDT by ConservativeMind
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To: ConservativeMind

The good news is that some vitamins and other supplements can help bolster ATP production. Exercise and sleep also help.

Imagine not getting any of those.


2 posted on 08/30/2021 9:56:38 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Thanks for posting this.


3 posted on 08/30/2021 10:14:55 PM PDT by laplata
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To: ConservativeMind

Cinnamon helps stabilize blood sugar levels, and helps prevent diabetes. It’s a good idea to take a couple of cinnamon pills before eating sugary food. Also, instead of sprinkling your food with sugar, try cinnamon powder.


4 posted on 08/30/2021 10:43:01 PM PDT by Angelino97
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To: ConservativeMind

[[The good news is that some vitamins and other supplements can help bolster ATP production]]

Do you know what they are off hand?


5 posted on 08/30/2021 10:48:26 PM PDT by Bob434
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To: Angelino97

[[It’s a good idea to take a couple of cinnamon pills before eating sugary food. ]]

Or combine cinnamon and sugar and eat cinnamon buns


6 posted on 08/30/2021 10:49:11 PM PDT by Bob434
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To: ConservativeMind

THIS is why. I ferment my sugar first......


7 posted on 08/30/2021 10:50:29 PM PDT by Organic Panic (Democrats. Memories as short as Joe Biden's eyes.)
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To: ConservativeMind
High uric acid and gout can be hereditary and nothing to do with sugar intake (as in me).
8 posted on 08/30/2021 10:52:40 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: ConservativeMind

bump


9 posted on 08/31/2021 2:47:42 AM PDT by gattaca ("Government's first duty is to protect the people, not run their lives." Ronald Reagan)
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To: ConservativeMind

bkmk


10 posted on 08/31/2021 3:06:48 AM PDT by sauropod (Bidet was no prize before he put the “d” in “dementia.” - Schlichter)
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To: ConservativeMind

If your liver is all full up with glycogen, then all the bad things happen when you eat fructose. If you have spare liver glycogen capacity, your liver converts the fructose to glucose, stores it as glycogen, and you’re good to go.

You maintain spare liver glycogen capacity by not eating too many carbohydrates.

Source: Dr. Lustig. (Sugar, the Bitter Truth guy).


11 posted on 08/31/2021 3:11:01 AM PDT by Born to Conserve
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To: ConservativeMind

Probably being added to the PRC’s “Social Credit” matrix. Imagine those billions keeping food diaries, daily blood sugar/weight/BP, and all such! An autocrat’s dream!

Done as an individual, it is fine, regimented for a population, it is BAD!


12 posted on 08/31/2021 4:28:08 AM PDT by SES1066 (Ask not what the LEFT can do for you, rather ask what the LEFT is doing to YOU!)
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To: ConservativeMind
"This shift in dietary trends, accompanied by a sedentary lifestyle, has been attributed to the rise in various metabolic disorders like diabetes, fatty liver disease, and heart disease."

Actually, while fostering the consumption of fatty foods (from frosting to fudge) sugar itself does little to add fat, unlike those food such have large percentages of fat calories, and accompanied by a sedentary lifestyle this is a killer. But for which Covid is often blamed. So forsake the chicken skin and you can have a soda (not artificially sweetened) and keep active or at least stay lean.

13 posted on 08/31/2021 4:47:24 AM PDT by daniel1212 ( Turn to the Lord Jesus as a damned+destitute sinner, trust Him to save + be baptized + follow Him!)
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To: ConservativeMind

Just lay off the soda pop and add years to your life. We drink water at meals. I have a friend who has been eating a pop tart and a diet coke for breakfast forever. She now has high blood pressure and type 2 diabetes. I do not.


14 posted on 08/31/2021 5:04:23 AM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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To: Bob434

More information, here:

https://www.naturalwellness.com/nwupdate/8-ways-to-fight-fatigue-and-increase-atp-production/

https://draxe.com/nutrition/adenosine/

https://draxe.com/health/mitochondria/

https://en.m.wikipedia.org/wiki/Ribose

Each of the above help create ATP in the body, but you can get it as a supplement, which may give similar benefits:

https://smile.amazon.com/s?k=atp&ref=nb_sb_noss


15 posted on 08/31/2021 7:16:10 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Georgia Girl 2

It sounds like she was keeping her calories low, but creating dysfunction that made her body have the same eventual effects she thought she was preventing.


16 posted on 08/31/2021 7:19:05 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Thanks, I be,even I have some kind of mitochondrial dysfunction, or a breakdown in how the body turns food I to fuel so every along the process. I note that at is mentioned a lot when trying g to research the issue


17 posted on 08/31/2021 8:36:50 AM PDT by Bob434
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To: ConservativeMind

Yep.


18 posted on 08/31/2021 2:31:17 PM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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