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Third COVID Vaccine Dose Could Be the Last
MedPage Today ^ | Aug 18, 2021 | Amanda D'Ambrosio

Posted on 08/18/2021 1:52:38 PM PDT by CondoleezzaProtege

Peter Hotez, MD, PhD, of Baylor College of Medicine in Houston, said on CNN Monday night that a 3-week interval between the first and second doses of Pfizer's mRNA vaccine, for instance, may not have been enough time to spur an extended immune response, with the initial shots acting only as a primary immunization.

An 8-month lag, on the other hand, could boost immunity significantly, Hotez said, with the potential to yield high levels of virus-neutralizing antibody and an immune response that is "really robust."

"That may be it for a while, we may not need annual boosters," Hotez said. "This could be the third and done."

Since it's typical for antibodies to wane over time, it's common for vaccines to be administered in multiple doses over a longer time period. People get three shots over a 6-month period for hepatitis B, for instance, and a four-dose regimen is recommended for polio.

"In fact, it is unusual to give a one-dose, give-and-go vaccine," John Moore, PhD, professor of microbiology and immunology at Weill Cornell Medicine in New York, told MedPage Today. "Most vaccines require at least two shots."

In a multi-dose vaccine regimen, a longer interval between doses gives the immune system time to mature, Moore said. During this time period, a process called affinity maturation takes place, which causes antibodies to improve in quality while dwindling in number, he said.

(Excerpt) Read more at medpagetoday.com ...


TOPICS: Health/Medicine
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To: xenia

1/3 is close to half?? You must have a really coarse ruler..


41 posted on 08/18/2021 3:51:58 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: xenia

Have you read the often-repeated partial, at least, explanation for this? That as the number of the unvaccinated decreases, the percentage of the disease appearing among the vaccinated will go up?

It was in the papers again today, for slow learners.

And the percentage here is still minuscule.

The slightly larger percentage in Israel seems to be partly that they started vaccinating on a large scale earlier and the vaccine loses strength over time, partly that the delta variant partly escapes the vaccine, partly that the Moderna seems to be more effective than the Pfizer against delta and with older people (who got vaccinated first), and partly that people are not being as careful as they were before they were vaccinated.


42 posted on 08/18/2021 3:54:41 PM PDT by firebrand ( )
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To: firebrand

I never tell people what to say. :-)


43 posted on 08/18/2021 3:55:12 PM PDT by cgbg (A kleptocracy--if they can keep it. Think of it as the Cantillon Effect in action.)
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To: xenia

That is totally untrue. You are obviously listening to the wrong radio broadcasts.


44 posted on 08/18/2021 3:56:00 PM PDT by firebrand ( )
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To: ThunderSleeps
just one more shot

Never trust a junkie!
45 posted on 08/18/2021 3:56:13 PM PDT by cgbg (A kleptocracy--if they can keep it. Think of it as the Cantillon Effect in action.)
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To: Organic Panic

You STILL don’t understand what “flatten the curve” means? It means don’t let the health system get overwhelmed, as it is now in Cuba, where people are going to the hospital essentially to die there, since there is no medicine.

We DID flatten the curve!

With the present surge we might not be so lucky, with all the resistance going on.


46 posted on 08/18/2021 4:00:12 PM PDT by firebrand ( )
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To: cgbg; Kevmo

It was Kevmo.


47 posted on 08/18/2021 4:08:24 PM PDT by firebrand ( )
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To: firebrand; cgbg

The anti-vaxxer ridiculous crowd was up & running long before this controversy came along. I’m pro-vax, but anti-mRNA forced-dosage-of-experimental-gene-sequence 666 whatever we’re calling this.


48 posted on 08/18/2021 4:16:43 PM PDT by Kevmo ( 600 political prisoners in Washington, DC. You cannot comply your way out of tyranny.)
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To: CondoleezzaProtege

Not buy it. We’ve gone from shelter in place for two weeks to just one more booster. They don’t know the science and who’s going to believe Biden now!


49 posted on 08/18/2021 4:27:35 PM PDT by DownInFlames (G)
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To: DownInFlames

Without Covid and the vaccines Biden’s got nothing to talk about. So it’ll be here and an active so called crisis his entire term.


50 posted on 08/18/2021 4:28:51 PM PDT by caww ( )
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To: monkeyshine

That’s what the Nurse Educator was saying was the difference between Israel’s current experience and the UK’s. Israel did vaccines like the US - 3 to 4 weeks apart. UK did 8-to-9 weeks or 11-to-12 weeks apart and their immunity seems to be stronger against Delta.

I can’t find the video, but here is the guy: https://www.youtube.com/channel/UCF9IOB2TExg3QIBupFtBDxg


51 posted on 08/18/2021 4:31:16 PM PDT by CrazyCatChick (But we know that when Christ appears, we shall be like him, for we shall see him as he is.)
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To: CondoleezzaProtege

BS.


52 posted on 08/18/2021 4:37:05 PM PDT by Captain Compassion (I'm just sayin')
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To: CondoleezzaProtege

Wish they could study this a bit more, from 1987

After experimental contamination of bovine raw and heat-
treated milks with bovine rotavirus and coronavirus strains, we
observed a strong viral inhibition only with raw milks, from
which virus recovery was 5 x 10^%. Between 30% and 80%
of the virus was recovered from the heat-treated milks, depend-
ing on the level of inoculation.


53 posted on 08/18/2021 6:00:55 PM PDT by pangaea6
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To: CondoleezzaProtege

It’s a killer of a shot.


54 posted on 08/18/2021 7:32:56 PM PDT by Old Yeller (We're a nation of surprisingly talented people run by the least talented of us.)
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To: CondoleezzaProtege

Its a flu shot.


55 posted on 08/18/2021 9:40:44 PM PDT by cp124 (Focus on treatment and not an experimental vaccine/flu shot.)
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To: firebrand

Are we doing human trials because Peta complained ?


56 posted on 08/18/2021 9:47:26 PM PDT by cp124 (Focus on treatment and not an experimental vaccine/flu shot.)
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To: srmanuel

The immunizations for infants / young children involve more than one booster shots to trigger permanent / long term immunity to things like measles, etc.


57 posted on 08/18/2021 10:11:28 PM PDT by Republican Wildcat
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To: Kevmo

You might have explained that instead of correction my diction.


58 posted on 08/19/2021 4:42:49 PM PDT by firebrand ( )
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To: firebrand

I’m pretty sure I did.


59 posted on 08/19/2021 4:48:46 PM PDT by Kevmo ( 600 political prisoners in Washington, DC. You cannot comply your way out of tyranny.)
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