The “severe Adverse Reactions” cited in the first link are such things as “fatigue”, “malaise”, temp of 101.5. The article also says that these reactions were limited to 2 days on average. It does not list any long term negative effects.
The toxicology link you gave pointed out that there are safe amounts of the saponin compound in foods. The first link, in the comments, points out that saponin occurs in root beer. Of course, ingesting a compound is different than injecting a compound. But, at any rate, it’s toxicity is not quite as bad as it sounds. The purpose of an adjuvant is to increase the immune response of the body. So it wouldn’t do to use salt water.
https://carnivoreaurelius.com/saponins/ (Slide)
Pro tip on how to reduce saponin content: Cook saponin containing foods in vegetable oils, then throw them in the trash.
This is why I recommend the carnivore diet. If you’re interested in a 30 day guide to getting started, make sure to sign up at the end of the article."
(If you like meat the site is for you!)