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Mystery Solved? Researchers Discover Biomarker That Predicts Who Will Suffer Severe Illness From COVID-19
PJ Media ^ | 08/11/2021 | Stacey Lennox

Posted on 08/11/2021 8:39:00 AM PDT by SeekAndFind

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To: aMorePerfectUnion

“I have taken the protocol that is now commonly known from the earliest outbreaks in the US...”

Which protocol was that?


21 posted on 08/11/2021 9:01:54 AM PDT by Rennes Templar (Come back, President Trump.)
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To: SeekAndFind
The Scientific Reports study by Besim Ogretmen, et al., is "Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID‑19 patients" and is available online.
22 posted on 08/11/2021 9:02:35 AM PDT by Carl Vehse
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To: HartleyMBaldwin

Vitamin D

As for foods to increase sphingosine: eggs, cheese, cream and sweet potatoes. Hmmm, sweet potatoes Au gratin? But don’t eat too much or the BMI will rise, and that’s not a good bio marker for severe Covid.


23 posted on 08/11/2021 9:03:14 AM PDT by FlyingFish
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To: SeekAndFind

Let’s see if this work gets recognized and extended or ignored as if it never happened.


24 posted on 08/11/2021 9:04:29 AM PDT by 2 Kool 2 Be 4-Gotten
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To: FlyingFish

Will fauci and ilk rush in to ban the tests because it will show that most everyone will be fine and won’t need vaccine?


25 posted on 08/11/2021 9:04:54 AM PDT by Bob434
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To: SeekAndFind

Interesting!

https://en.wikipedia.org/wiki/Sphingosine


26 posted on 08/11/2021 9:08:53 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion, or satire. Or both.)
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https://en.wikipedia.org/wiki/Sphingolipid


27 posted on 08/11/2021 9:10:01 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion, or satire. Or both.)
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“Sphingolipids are commonly believed to protect the cell surface against harmful environmental factors by forming a mechanically stable and chemically resistant outer leaflet of the plasma membrane lipid bilayer. Certain complex glycosphingolipids were found to be involved in specific functions, such as cell recognition and signaling. Cell recognition depends mainly on the physical properties of the sphingolipids, whereas signaling involves specific interactions of the glycan structures of glycosphingolipids with similar lipids present on neighboring cells or with proteins.”

https://en.wikipedia.org/wiki/Sphingolipid#Functions_of_mammalian_sphingolipids


28 posted on 08/11/2021 9:12:34 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion, or satire. Or both.)
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To: Arkansas Tider

The common thread seems to be to keep inflammation under control.


29 posted on 08/11/2021 9:12:57 AM PDT by rightwingcrazy (;-,)
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To: HartleyMBaldwin; BiglyCommentary; All
"Conversely, elevated levels of sphingosine, as well as a protein involved in its production, acid ceramidase (AC) [emphases added], are associated with asymptomatic infections."
"Are there nutritional supplements that will increase sphingosine and other sphingolipid levels?"

This is way, way out of scope of anything that I've ever studied, but a duckduckgo search seemingly questions vitamin D3 in connection with production of chemicals sphingosine and acid ceramidase.

"In this study, we tested the hypothesis that vitamin D supplementation would alter circulating long-chain ceramides and related metabolites involved in sphingolipid [emphases added] metabolism in humans." -- Vitamin D3 Supplementation Increases Long-Chain Ceramide Levels in Overweight/Obese African Americans: A Post-Hoc Analysis of a Randomized Controlled Trial (4.2.20)

I don't know what the conclusion was.

Corrections, insights welcome.

30 posted on 08/11/2021 9:16:39 AM PDT by Amendment10
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To: SeekAndFind

Drink milk.

In that regard I am a 70+ year old kid, having never lost my appreciation for milk.


31 posted on 08/11/2021 9:18:24 AM PDT by Wuli
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To: SeekAndFind

https://www.sciencemag.org/news/2014/02/black-death-left-mark-human-genome

The Black Death didn’t just wipe out millions of Europeans during the 14th century. It left a mark on the human genome, favoring those who carried certain immune system genes, according to a new study. Those changes may help explain why Europeans respond differently from other people to some diseases and have different susceptibilities to autoimmune disorders.


Those with the right genetic background survived. The survival genetic information existed. The plague killed those that didn’t have it. There most likely was environmental and nutritional factors. It is selection not mutation of existing gene information. Genetic selection is a much better word than mutation. We learned this basis stuff in science 101 with Mendel.

I call this devolution, we lost genetic information but there is some theory that all the junk DNA still has it and is still available if needed. Tremendous design.


32 posted on 08/11/2021 9:22:55 AM PDT by PeterPrinciple (Thinking Caps are no longer being issued but there must be a warehouse full of them somewhere.)
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To: HartleyMBaldwin

Based on further reading; eggs, beef, chicken, cheese, butter, cream and soybeans All contain relatively high levels of it. It is also found in the body in LDL and VLDL cholesterol. Studies show it is also an important mediator of colon cancer and atherosclerosis.


33 posted on 08/11/2021 9:23:47 AM PDT by redangus
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To: SeekAndFind

Interesting.


34 posted on 08/11/2021 9:26:28 AM PDT by Robert DeLong
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To: Arkansas Tider

Could you send a link to the study to which you are referring? TIA.


35 posted on 08/11/2021 9:28:19 AM PDT by FamiliarFace
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To: FamiliarFace

https://www.nature.com/articles/s41598-019-55199-3


36 posted on 08/11/2021 9:36:04 AM PDT by Arkansas Tider (Army EOD (Ret))
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To: Buttons12

I was thinking poke salad, myself.


37 posted on 08/11/2021 9:36:19 AM PDT by Kenny500c ( )
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To: FlyingFish; Brian Griffin; RayChuang88

The “comorbidity” thing is a crock of shit.

Do you know what the mysterious link is between all those things? They are people that dont get outside much and have poor diets especially too many processed carbs.

Im in a medical related field, do you know who isnt coming in to work due to cooties? The young urban activity and diet sit in the basement and play on my phone/game system and eat dorritos crowd.

Do you know who is coming to work without symptoms and doing all the entry level work along with theirs? Rural (Wisconsin) 50+yo overweight diabetic chain smokers whos diets would include large amounts of eggs, cheese, cream, whole milk (vitD), and pickled herring (vitD) that spend their spare time working a small farm, hiking, fishing, wildcrafting and other outdoor activities.

Its not magic people, some have been saying this the whole time.


38 posted on 08/11/2021 9:38:39 AM PDT by gnarledmaw (Hive minded liberals worship leaders, sovereign conservatives elect servants.)
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To: Codeflier

LOL. I’m an old white female who loves cats and my doc thinks my immune system is so strong I probably don’t need vax.

I would, however, like to know what to do to get this stuff


39 posted on 08/11/2021 9:56:10 AM PDT by Veto! (Political Correctness Offends Me)
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To: FlyingFish

As for foods to increase sphingosine: eggs, cheese, cream and sweet potatoes.


Good to know. Thanks


40 posted on 08/11/2021 10:02:24 AM PDT by Faith65 (Isaiah 40:31 )
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