Shouldn't this be expected? I would need explanation from someone trained in the field but I thought for the most part the lasting immunity comes from memory T-cells that remember how to create antibodies, not specifically just from antibodies present in the blood. My understanding was that the antibodies show a positive reaction to infection, but the body remembers it long after the antibodies leave. I am open to corrections or clarifications.
You have it correct. The body retains a memory to respond as necessary but doesn’t register detectable anti-bodies beyond the year-long study from Finland.
T-cells may but have a similar testing regimen under the same timeframe.
Most Americans have natural immunity. Estimates are fully one-third already had the virus whether they are aware or not.
Avoid the vax. It’s experimental, demonstrates problems with blood clotting and smaller ones undetected are even more problematic long term.
The damage to the hearts of young people is especially tragic. It’s permanent.
Again, do not take the vax.
It should and I think this study upholds that view.
It also tentatively adds to the position severe disease means higher future immunity than mild/asymptomatic disease and that even wild acquired immunity (age-dependent and possibly sex dependent) has reduced resistance to stronger variants, that is, no apparent advantage for prior asymptomatic infection over vaccines.
” higher mean N-IgG, SFL-IgG and IgG-RBD concentrations in subjects who had recovered from severe disease than in those with mild disease six months after infection (p<0.001; Figure 3). The difference was 2.0 to 7.4-fold, depending on the age group, and persisted for at least twelve months after infection” Further down it says that it was males in the mild infection category that saw the largest drop.
“the subjects recovered from severe disease had overall 2.1 to 3.0-fold NAb titers compared to those with mild disease “
“Even though NAbs persist relatively long in most subjects, neutralization efficiency against Alpha (B.1.1.7), Beta (B.1.351) and Delta (B.1.617.2) variants was decreased compared to the wild-type virus. This was emphasized in subjects who had recovered from mild disease which is concerning since mild symptomatic individuals represent the majority of COVID-19 cases (1). Indeed, NAbs may not be developed in mild symptomatic or asymptomatic individuals and may also wane relatively quickly after infection (31).