[SeekAndFind]

CLICK THIS LINK FOR THE COMPLETE DESCRIPTION OF THE STUDY

[Truthoverpower]

Silver works against all viruses and bacteria

[SeekAndFind]

Table 1 Baseline characteristic of the study population.

	Control (n = 15)	Ivermectin (n = 30)	P value
Age (year)	38•1 ± 11•7	42•3 ± 12•8	0•29
Gender
Female	5 (33%)	15 (50%)	0•29
Male	10 (67%)	15 (50%)
Weight (kg)	79•7 ± 14•4	75•3 ± 15•0	0•35
Overweight	8 (53%)	6 (20%)	0•05
Obesity I	2 (13%)	11 (37%)	0•20
Obesity II	1 (7%)	1 (3%)	0•79
Obesity III	1 (7%)	1 (3%)	0•79
Oxygen saturation <94%	0	1 (3%)	0•63
Log viral load (log10 copies/reaction)	5•39 ± 1•56 (n = 12)	4•18 ± 1•60 (n = 20)	0•05
Hematology
White blood cell count (cell/µL)	4857 ± 1874	6014 ± 2402	0•09
Lymphocyte count (cell/µL)	1478 ± 266	1744 ± 747	0•09
Biomarkers
Lactate dehydrogenase (IU/L)	460 ± 117	468 ± 140	0•85
Ferritin (mg/dL)	1318 ± 1969	1071 ± 1304	0•66
D-dimer (µg/mL)	1•5 (0•1–2•8)	1•5 (0•5–1•8)	0•82
Time from symptoms onset (day)	3•6 ± 1•4	3•5 ± 1•0	0•78
Body temperature ≥37•5 °C	1 (7%)	4 (13%)	0•70
WHO-ordinal scale
3	13 (87%)	29 (97%)	0•20
4	2 (13%)	1 (3%)
Ground glass opacities in thoracic imaging	6 (40%)	14 (47%)	0•67
Comorbidities
Hypertension	3 (20%)	3 (10%)	0•35
Diabetes	1 (7%)	6 (20%)	0•24
Chronic lung disease/Asthma	1 (7%)	4 (13%)	0•50

Numeric variables are reported as median (IQR) or mean ± standard deviation• Categoric variables are reported as counts (%). Overweight: Body mass index (BMI) 25–29•9 kg/m2; Obesity I: BMI 30–34•9 kg/m2; Obesity II: BMI 35–39•9 kg/m2; Obesity III: BMI >40 kg/m2.

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  Fig. 2 Viral load by quantitative RT-PCR on upper respiratory tract secretions since baseline in patients receiving IVM 0•6 mg/kg/day for 5 days versus untreated controls.

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  Fig. 3: Viral load reduction between baseline and day-5 (median and IQR) in untreated controls and IVM treated patients discriminated by their median IVM plasma concentrations

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  Fig. 4 Viral load decay rates by quantitative RT-PCR on upper respiratory tract secretions in untreated controls and IVM treated patients according to median plasma concentrations of IVM. Data are expressed as median (IQR)

[SeekAndFind]

Ping for your interest

[BrexitBen]

The Fauci/WHO/CDC/CCP coverup cannot sustain itself much longer.

Ivermectin has ALWAYS been the proven, safe, cheap remedy for this Wuhan Virus.

[Qiviut]

Just watched a podcast with an excellent discussion on Ivermectin & meta analysis of studies regarding Ivermectin ... Dr. Tess Lawrie & Bret Weinstein (Dark Horse):

https://odysee.com/@BretWeinstein:f/TessLawrie:0

Tess Lawrie is an MD and PHD, external analyst for the World Health Organization, and an expert in analysis of medical evidence

Dark Horse has been demonitized by Youtube so they are posting video on Odysee. This video buffered twice (long buffers, but it came back both times). Lots of complaints in the comments about video (buffering, audio, etc.). Except for the two buffering spots, it played fine for me. I did look on the youtube channel & this video is not there.

[Mom MD]

The money quote

No differences in clinical evolution at day-7 and day-30 between groups were observed.

[jonrick46]

“In summary, our findings support the hypothesis that IVM has a concentration dependent antiviral activity against SARS-CoV-2 and provides insights into the type of evaluations to be considered in the assessment of antiviral drugs for the control of COVID-19. Follow-up trials to confirm our findings and to identify the clinical utility of IVM in COVID-19 are warranted.”

I looks like ivermectin research is heading to some promising developments:

“Follow-up trials to confirm our findings and to identify the clinical utility of IVM in COVID-19 are warranted.”

[catnipman]

“.6 mg/kg/day for 5 days”

that’s only slightly higher than the Zelenko protocol at 0.4-0.5mg/kg/day for 5-7 days

[ransomnote]

Apparently, the Lancet got caught lying earlier and quietly retracted their ‘piece’ after it had done it’s job. So now, the Lancet is not much better than CNN or New York Times. They lie.

[Pollard]

high-dose IVM in 45 COVID-19 hospitalized patients

Not supposed to wait until hospitalized. Supposed to take it as soon as a positive test or symptoms

[ProtectOurFreedom]

The summary above does not discuss dosage needed to achieve the plasma IVM concentrations listed. The paper says...

IVM 6 mg ranurated tablets were used in all cases at a dose of 600 µg/kg/day based on baseline weight rounding to the lower full (6 mg) and half (3 mg) dose. The regimen of 600 µg/kg for 5 days was selected based on the in-vitro data suggesting the need for higher doses than for current indications of IVM, the available data on the safety of this dose in regimens of up to 3 days (either in fast or fed state) and the available information on the PK of IVM, predicting the lack of significant accumulation of IVM after 5 daily doses.

600 µg/kg/day is about triple the dose recommended in other papers.

The Italian RC trial COVidIVERmectin: Ivermectin for Treatment of Covid-19 was going to test ivermectin 600 μg/kg daily for 5 consecutive days + placebo and ivermectin 1200 μg/kg daily at empty stomach with water for 5 consecutive days. Recruitment was terminated because disease incidence has dramatically dropped and there is lack of eligible patients. The study ended June 23, 2021. It isn't clear if the study was completed with the enrolled patients or if it was aborted before completion.