The doctor pointed out that d-dimer is not completely diagnostic by itself.
On the other hand, your assertion that it is triggered by inflammation in general seems at odds with this description of the test. It seems very specific to formation and breakdown of clots. Can you cite a reference that refutes the content of this article?
https://labtestsonline.org/tests/d-dimer
I can site 20 years of clinical experience — D-dimer is non-specifically elevated in almost all inflamed states. Sepsis, post surgical , you name it, if you are inflamed your D-dimer is elevated.
In the Covid era, we use it exactly as a marker of inflammation and to determine if anticoagulation should be considered, specifically.
If you want to know what is going on at the capillary level and if we are worried about microcirculatory thrombosis — what you would be looking for is schistocytes on peripheral smears, and FSPs.
D-dimer is pretty non-specific and goes off the rails in many conditions.