[ETCM]

- "From December 14, 2020, to February 28, 2021, we used data from the "v-safe after vaccination health checker" surveillance system, the v-safe pregnancy registry, and the Vaccine Adverse Event Reporting System (VAERS) to characterize the initial safety of mRNA Covid-19 vaccines in pregnant persons".

- "Among 3,958 participants enrolled in the v-safe pregnancy registry, 827 had a completed pregnancy, of which 115 (13.9%) resulted in a pregnancy loss and 712 (86.1%) resulted in a live birth (mostly among participants with vaccination in the third trimester)."

Now it doesn't take a genius to figure out 3 things from this data.

- First, these women had only been enrolled in this study 1-3.5 months when this was written. To have given birth already, the participant would have had to be AT LEAST late in her 2nd trimester when vaccinated. Note that this data was collected MARCH 30. Those who already delivered were almost all in their 3rd trimester when vaccinated.

- Second, 104 miscarriages out of 3,959 pregnancies isn't 82%. Applying normal miscarriage rates, about 10%-15%, to the 1132 vaccinated during the first trimester and 92 vaccinated before conception, we should expect 122-184 miscarriages.

- Third, the vast majority of these women, over 3,000 were STILL pregnant when this study was written. The 827 "completed pregnancies" are a fraction of the participants. In December, the study will be completed.

[Triple]

Ok ...

Read and explain the ✝️and Following footnote to table 4. - TIA

[DugwayDuke]

ETCM wrote: “Second, 104 miscarriages out of 3,959 pregnancies isn’t 82%. Applying normal miscarriage rates, about 10%-15%, to the 1132 vaccinated during the first trimester and 92 vaccinated before conception, we should expect 122-184 miscarriages.”

IOW, there were fewer than expected miscarriages than would have been expected?

[Triple]

Do you get 96/127 early pregnancies spontaneously terminated for women in the study, or are you saying that there are many other women In The study, with early jabs, and they are still pregnant.

If that is the case (this group is still pregnant), then This was written very poorly, and the dataset is premature to publish.

[Triple]

I’m not sure you first dash is correct.

See Table S4. (Help needed)

Here: https://www.nejm.org/doi/suppl/10.1056/NEJMoa2104983/suppl_file/nejmoa2104983_appendix.pdf

It looks like this table says (including the notes) that 37 out of the 81 first trimester vax moms that had completed pregnancy, had miscarriages. (About twice the expected rate of miscarriage)

Your interpretation please...

Characteristics of reports to VAERS among pregnant persons following mRNA COVID-19 vaccines, December 14,2020–February 28, 2021 (N=221)*.
Median maternal age in years (range)
Trimester of pregnancy at time of vaccination in completed weeks†
First (0–13 weeks) Second (14–27 weeks) Third (28+ weeks)
Vaccine brand (%)
Pfizer-BioNTech Moderna
Most frequently reported nonpregnancy-specific adverse events (%)‡ Fatigue
Headache
Chills
Pain in extremity Nausea
Pain
Fever
Injection site pain Dizziness
Injection site erythema
Pregnancy- or neonatal- specific conditions (%)
Miscarriage§
Stillbirth
Premature rupture of membranes
Vaginal bleeding
Fetal hydrops
Preterm delivery
Neonatal death in 22-week preterm birth║ Other¶
33 (16–51)
163
81 (49.7) 53 (32.5) 29 (17.8)
130 (58.8) 90 (40.7)
155 (70.1)
44
43
30
27
25
21
18
17
17
11
66 (29.9)
46 3 3 3 2 2 1 6
* Reports received and processed through February 28, 2021; 1 report with unknown vaccine brand
† Includes 163 reports where information was available on trimester of pregnancy at the time of vaccination
‡ Not mutually exclusive; more than one adverse event can be assigned to a single report
§ 37 in first trimester, 2 in second trimester, and 7 where trimester was unknown or not reported
║ Person was diagnosed with COVID-19 before pregnancy (mild 3-day illness 8 months before delivery) and received dose 2 of Pfizer-BioNTech vaccine one day prior to delivery; onset of
8

preterm labor symptoms began 2 days before dose 2 and birth occurred 32 hours after dose 2 at 22 weeks and 2 days; reported symptoms following receipt of dose 2 were muscle aches and chills; additional information regarding any adverse events associated with dose 1 of the vaccine were not available
¶ Other pregnancy- or neonatal-specific conditions include 1 report each of calcified placenta, leakage of amniotic fluid, shortened cervix, gestational diabetes, pre-eclampsia, irregular/painful contractions

[House Atreides]

Wow… a poster who actually understands the math. Thanks for posting.