One would have to be built to rotate opposite the other.
I think the super charger location may have been an issue. I don’t think the speed would have improved much. The Lightening was aptly named and the later models could hit 450 mph and push the sound barrier in a dive.
Since the Lancaster, and Mosquito bombers used that engine they had them turned both ways.
Another funny what if: What if the British had bought a right to manufacture the 2000 HP, Pratt and Whitney Double Wasp engine that was used in the F4U Corsair and F6F Hell Cat and strapped one on to the front of a Hawker Hurricane?