Existing antihistamine drugs show effectiveness against COVID-19 virus in cell testing

University of Florida ^ | Dec 2020

[CondoleezzaProtege]

Research funding was provided by the UF Clinical and Translational Science Institute, the University of California San Francisco Clinical & Translational Science Institute, the National Institutes of Health and the Center for Data Driven Insight and Innovation at University of California Health.

[Trumpisourlastchance]

Good stuff, thanks for posting.

Pharma will try to deep six this of course.

[DannyTN]

Good to know.

Of the three I’ve only used benadryl. Causes drowsiness. Long term use causes hypertension.

[wildcard_redneck]

Now they will start banning antihistamines by requiring prescriptions for them.... “We cannot trust the proles with these powerful medicines, they could hurt themselves.”

[Carriage Hill]

hydroxyzine, diphenhydramine and azelastine

Atarax and Benadryl... what’s the 3rd OTC product’s name?

[shotgun]

I always take a form of an antihistamine prior to wine tasting events. keeps my nose from getting stuffy.

[E. Pluribus Unum]

I bet pseudoephedrine works even better but they didn’t test it because it can be used to synthesize methamphetamine.

[FamiliarFace]

It’s not OTC. Right now it’s prescription only.

Brand names in the US are Astelin, Astelin Ready-Spray, and Astepro

https://www.mayoclinic.org/drugs-supplements/azelastine-nasal-route/description/drg-20068252

[Magic Fingers]

“hydroxyzine, diphenhydramine and azelastine
Atarax and Benadryl... what’s the 3rd OTC product’s name?”

Azelastine is prescription, not OTC. It’s just called azelastine (I’m looking at a bottle).

[Carriage Hill]

Thanks.

[FamiliarFace]

*** Drugs that bind ACE2 could change disease outcomes, so she asked Ostrov to develop a list of small-molecule drug candidates.***

Famotidine also binds ACE2. It is commonly sold under the name Pepcid-AC.

Although it’s on label approval is as an antacid, my doctor has me take it in addition to a Benedryl tablet when I start to break out in hives and itching. So far, it’s worked like a charm the couple of times I’ve needed to do that. I do have an epi-pen just in case, but I hope to never need to use that.

I have often wondered if a good treatment for CoVid19 would be with a nasal spray. Seems like it would target the right area quickly.

[CondoleezzaProtege]

I’ve heard the combination being prescribed also for people suffering side effects from the vaccines.

[FamiliarFace]

I hadn’t heard that, but it wouldn’t surprise me.

I manage most of the time with Flonase nasal spray and then Zyrtec, Allegra, and Claritin on rotation if I need more. I jump to the Pepcid AC/Benadryl combo only when necessary.

[jimtorr]

I use Flonase. I wonder if that helps?

[lil'bit]

Hydroxyzine (Atarax) is not OTC. I have a prescription for it.

[Carriage Hill]

Go it. So Benadryl is the only OTC?

[Vendome]

antihistamine medications are always effective against flu effects...

[metmom]

H2 blockers are recommended for people with some allergic type conditions.

The doctors want me on it as a histamine blocker but the one I tried I reacted very badly to.

I should be in great shape with the amount of antihistamines I pop every day. I am so glad the stuff can be had cheaply OTC at Sam’s and BJs.

[EBH]

All for want of a nail...

Wouldn’t it be something that Benadryl could have saved millions of lives?

For want of a nail the shoe was lost.
For want of a shoe the horse was lost.
For want of a horse the rider was lost.
For want of a rider the battle was lost.
For want of a battle the kingdom was lost.
And all for the want of a horseshoe nail.

[FamiliarFace]

I use Flonase almost every day, but not quite. It really helps with my many environmental allergies. Between that and the other vitamins and supplements I’ve been taking every day since April 2020, I’ve had barely a sniffle. I feel pretty darn good most days.