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Could mRNA Vaccines Permanently Alter DNA? Recent Science Suggests They Might.
Research on SARS-CoV-2 RNA by scientists at Harvard and MIT has implications for how mRNA vaccines could permanently alter genomic DNA, according to Doug Corrigan, Ph.D., a biochemist-molecular biologist who says more research is needed.

https://sciencewithdrdoug.com/2020/11/27/will-an-rna-vaccine-permanently-alter-my-dna/

I believe this is the study he is referring to.

https://www.biorxiv.org/content/10.1101/2020.12.12.422516v1.full.pdf

SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome
2 Liguo Zhang1, Alexsia Richards1, Andrew Khalil1, 2, 3, Emile Wogram1, Haiting Ma1, Richard A.
3 Young1, 4, Rudolf Jaenisch1, 4, #
4
5 1Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
6 2John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge,
7 MA, USA.
8 3Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA,
9 USA.
10 4Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
11 #Correspondence: jaenisch@wi.mit.edu
12 13
14 Summary 15
16 Prolonged SARS-CoV-2 RNA shedding and recurrence of PCR-positive tests have been
17 widely reported in patients after recovery, yet these patients most commonly are non-infectious1-
18 14. Here we investigated the possibility that SARS-CoV-2 RNAs can be reverse-transcribed and
19 integrated into the human genome and that transcription of the integrated sequences might
20 account for PCR-positive tests. In support of this hypothesis, we found chimeric transcripts
21 consisting of viral fused to cellular sequences in published data sets of SARS-CoV-2 infected
22 cultured cells and primary cells of patients, consistent with the transcription of viral sequences
23 integrated into the genome. To experimentally corroborate the possibility of viral retro-
24 integration, we describe evidence that SARS-CoV-2 RNAs can be reverse transcribed in human....