Two questions, please:
Am I correct in that most traditional vaccines use “dead” pathogens to stimulate the body’s defenses? And if that is so, why not just use dead COVID-19 viruses in vaccines, instead of messing around with DNA and RNA?
‘Am I correct in that most traditional vaccines use “dead” pathogens to stimulate the body’s defenses?’
some use attenuated pathogens...
Yes- traditional vaccines are dead pieces of viral protein.
Your body identifies them as foreign, and makes antibodies.
Why not this path?
A really tough question...
It was tried on other related coronavirus and failed. (Mers &sars)
Coronavirus is likely to cause ADE. Antibody-dependent enhancement.
This effectively is fatal for someone that is vaccinated- that is then exposed to the virus in the wild.
Perhaps this mechanism reduces the chances for ADE, my speculation.
Also - these vaccines have “other new ingredients” that increase uncertainty.
Bottom line- I don’t know why this approach is being taken, but it is dangerous, in my opinion.
This adenovirus gene therapy approach is turned down by people with severe genetic disease, due to the risk. (hemoglobin mutation) See B thalassemia.
Because there arent any coronavirus vaccines....
Otherwise we’d have defeated the common cold