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Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus
PLOS ONE ^ | 01/31/2012 | Chien-Te Tseng, Elena Sbrana, Naoko Iwata-Yoshikawa, Patrick C. Newman, Tania Garron, Robert L. Atma

Posted on 01/29/2021 1:41:02 PM PST by Jan_Sobieski

Background

Severe acute respiratory syndrome (SARS) emerged in China in 2002 and spread to other countries before brought under control. Because of a concern for reemergence or a deliberate release of the SARS coronavirus, vaccine development was initiated. Evaluations of an inactivated whole virus vaccine in ferrets and nonhuman primates and a virus-like-particle vaccine in mice induced protection against infection but challenged animals exhibited an immunopathologic-type lung disease.

Design

Four candidate vaccines for humans with or without alum adjuvant were evaluated in a mouse model of SARS, a VLP vaccine, the vaccine given to ferrets and NHP, another whole virus vaccine and an rDNA-produced S protein. Balb/c or C57BL/6 mice were vaccinated IM on day 0 and 28 and sacrificed for serum antibody measurements or challenged with live virus on day 56. On day 58, challenged mice were sacrificed and lungs obtained for virus and histopathology.

Results

All vaccines induced serum neutralizing antibody with increasing dosages and/or alum significantly increasing responses. Significant reductions of SARS-CoV two days after challenge was seen for all vaccines and prior live SARS-CoV. All mice exhibited histopathologic changes in lungs two days after challenge including all animals vaccinated (Balb/C and C57BL/6) or given live virus, influenza vaccine, or PBS suggesting infection occurred in all. Histopathology seen in animals given one of the SARS-CoV vaccines was uniformly a Th2-type immunopathology with prominent eosinophil infiltration, confirmed with special eosinophil stains. The pathologic changes seen in all control groups lacked the eosinophil prominence.

Conclusions

These SARS-CoV vaccines all induced antibody and protection against infection with SARS-CoV. However, challenge of mice given any of the vaccines led to occurrence of Th2-type immunopathology suggesting hypersensitivity to SARS-CoV components was induced. Caution in proceeding to application of a SARS-CoV vaccine in humans is indicated.

(Excerpt) Read more at journals.plos.org ...


TOPICS: Conspiracy; Health/Medicine; Reference
KEYWORDS: chinavirusvaccine; coronavirus; covid19; sideeffects; vaccination; vaccine; vaccinedeaths
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10 years of Coronavirus (SARS) Vaccine trials game researchers the following:

1. Protection against the original virus

2. Hypersensitivity to all future Coronaviruses

3. Death of the animal test subjects

1 posted on 01/29/2021 1:41:02 PM PST by Jan_Sobieski
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To: Jan_Sobieski

MODERATOR: the date should be changed to 2012


2 posted on 01/29/2021 1:42:04 PM PST by Jan_Sobieski (Sanctification)
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To: Jan_Sobieski

Some of the deaths in Wuhan were people who the trial Vaccine before the current outbreak. There was some leak stories about this last March.


3 posted on 01/29/2021 1:46:13 PM PST by DEPcom (Impeach Illegitimate Biden/Harris )
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To: Jan_Sobieski

So much of this needs to be exposed for fraud. The virus is real, but has been highly exagerated and used for nefarious gain

https://rumble.com/embed/vad6k1/?pub=4&fbclid=IwAR1APl5HU6J06mqs4VjSMO0jPjjezRr2UMhVXe9OE4TWqTIx_rkbwGj5GJI

Great video


4 posted on 01/29/2021 1:46:40 PM PST by patriot torch (Ashlie Babbitt-say her name)
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To: patriot torch

Soory Jan. I was implying how the covid virus was being used.


5 posted on 01/29/2021 1:47:55 PM PST by patriot torch (Ashlie Babbitt-say her name)
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To: DEPcom

Test run?


6 posted on 01/29/2021 1:47:55 PM PST by Jan_Sobieski (Sanctification)
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To: patriot torch

Sure. I agree! From this research paper, I am much more concerned about the Vaccine than the Virus! (no vaccine for my family)


7 posted on 01/29/2021 1:49:55 PM PST by Jan_Sobieski (Sanctification)
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To: Jan_Sobieski

Yep. Here’s another researcher saying, in essence, the current covid vaccine is setting up the recipients to die when they are “challenged” by the real virus. It should protect you in your younger years, but causes the body to attack itself like arthritis. When you develop another co-morbidity in your advanced years, you will die from it.

https://citizenfreepress.com/breaking/professor-of-molecular-genetics-issues-chilling-warning-on-covid-mrna-vaccines/


8 posted on 01/29/2021 1:50:50 PM PST by Gen.Blather (Wait! I said that out loud? )
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To: Jan_Sobieski

Yes.

I’ve pointed these studies out here since the beginning of the Wuhan flu.

I’m not sure there is evidence this delayed response is occurring due to the current vaccines, but it is something to monitor.


9 posted on 01/29/2021 1:54:58 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: Jan_Sobieski

Fools rush in where angels fear to tread. I’m giving the vaccine a year of public distribution before joining the experiment. Using Vitamin D 1000u and Zinc with Quercetin will continue to work fine for me in the meantime.

Now that even the AMA has found HCQ+Zinc+AZ to be beneficial for symptomatic patients there’s no rush.


10 posted on 01/29/2021 1:56:55 PM PST by Dave Wright
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To: Dave Wright

Might want to wait 2-3 years just to be safe


11 posted on 01/29/2021 1:58:15 PM PST by Jan_Sobieski (Sanctification)
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To: Jan_Sobieski

12 posted on 01/29/2021 2:03:33 PM PST by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
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To: ifinnegan
I'm not sure there is evidence this delayed response is occurring due to the current vaccines, but it is something to monitor.

I recall a couple of articles from 9 or ten months ago theorizing why the COVI19 death rate was so high in Italy. It was speculated that many in Italy had taken the SARS vaccine in the early 2000s; which had negative long-term effects on the immune system.

13 posted on 01/29/2021 2:11:36 PM PST by suijuris (Once a man learns to see he finds himself alone in the world with nothing but folly.)
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To: Jan_Sobieski

Now they say something?
Will have to wait until spring to see what happens to all the vaxxed subjects when they get exposed again.


14 posted on 01/29/2021 2:21:35 PM PST by silverleaf (In a time of universal deceit, telling the truth is a revolutionary act.)
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To: Jan_Sobieski

https://www.bitchute.com/video/OtrXxlBk4j6m/?fbclid=IwAR1Rwl-8ozNQ9bEn4NAJHZ-UkeLoVgkPEos5BPEvn54NLxAtNejkmJnh3ZQ

This link is to a new interview of Dr Judy Merkovitz. I watched it earlier today. I WILL NEVER ACCEPT THIS “VACCINE”.


15 posted on 01/29/2021 2:23:07 PM PST by upsdriver
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To: Dave Wright
Increase your vitamin D to 10,000 IU per day.

The "disinfectant" used by the body is Cathelicidin , which depends on sufficient vitamin D levels. "Decreased production of cathelicidin antimicrobial protein-18 (hCAP18) has been proposed to be a key mechanism linking decreased 25-hydroxyvitamin D (25D) levels with adverse outcomes among critically ill patients."

Cathelicidin antimicrobial protein, vitamin D, and risk of death in critically ill patients

:

“Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study”

"Eligible patients were allocated at a 2 calcifediol:1 no calcifediol ratio through electronic randomization on the day of admission to take oral calcifediol (0.532 mg), or not. Patients in the calcifediol treatment group continued with oral calcifediol (0.266 mg) on day 3 and 7, and then weekly until discharge or ICU admission."

So the initial dose was equivalent to about 20,000 IU of Cholecalciferol, followed by 10,000 IU on days 3 and 7 and every week thereafter. Assuming a stay of 14 days, this would mean a total of 532+266*3= 1330 mcg of calcifediol. The cost of calcifediol is about $1,100 for a bottle of 30 30mcg capsules. So a full course of treatment would cost about $1700 at retail prices.

A possible alternative is to take 10,000 IU of Cholecalciferol every day for a year (instead of waiting to catch the Chinese Virus). At current prices, that would cost less than $100. If you start now, you might be effectively "immune" by the time you are exposed to a significant viral load.


16 posted on 01/29/2021 2:29:30 PM PST by Ragnar54 (Obama replaced Osama as America's worst enemy and Al Qaeda's financier)
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To: Gen.Blather

Also on jameslyonsweiler.com from December 6, 2020 “Susceptibility of People to Pathogenic Priming is a Prime Reason to Eschew Covid 19 Vaccine Mandates”. Yet another source of the same thing.


17 posted on 01/29/2021 2:29:41 PM PST by packagingguy
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To: packagingguy

Ezekiel Jonathan “Zeke” Emanuel is Biden’s medical policy adviser. He has repeatedly said that anyone over 65 should be denied medical care. It looks as if many people vaccinated for Covid will be primed to die decades before their time, but after age 65. Convenient, eh?


18 posted on 01/29/2021 2:37:45 PM PST by Gen.Blather (Wait! I said that out loud? )
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To: Jan_Sobieski

it’s a different vaccine. mRNA is new, this trial was a VLP or Virus-Like Protein with or without aluminum adjuvant. Totally different animal.

I’m holding off on any vaccine right now. I’m just getting over SARS/pneumonia; I didn’t have an antibody response to the virus. tested positive twice two weeks apart.

How will a vaccine work then?


19 posted on 01/29/2021 3:16:40 PM PST by normbal (normbal. somewhere in socialist occupied America)
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To: Gen.Blather

Gen.Blather wrote: “Yep. Here’s another researcher saying, in essence, the current covid vaccine is setting up the recipients to die when they are “challenged” by the real virus. It should protect you in your younger years, but causes the body to attack itself like arthritis. When you develop another co-morbidity in your advanced years, you will die from it.”

The professor in the video stated: “Normally, because the mRNA is in every cell of their body, it’s almost unstoppable. It destroys the heart, or the spleen, or the lungs, or the liver because the mRNA is expressing the protein in every cell.”

So what? The mRNA causes the body to produce antibodies to the virus just like one would produce antibodies after an infection. IOW, anyone who has had CV19 would face these same issues. BTW, the mRNA does not remain in the body nor does it modify a persons DNA. So what’s the point other than more fear pornograph?


20 posted on 01/29/2021 3:22:09 PM PST by DugwayDuke (We deeply regret any inconveniences cause by the pandemic.)
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