And the great lie is...?
Probably that a good life can just given to you. The truth is that everything must be earned.
The great truth is: If you live a pathological life, then you pathologize society.
Basically, that you are worthless, and the problem is everybody else, and that there is nothing you can do about your worthlessness.
He’s referring to refusing to tell the lies that tyrannies impose on us. Praising the incompetent leaders, denying atrocities ... or in the modern context, that a dude in a dress is a woman because he says so, and you’re a meanie if you don’t use his preferred pronouns.