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To: Uncle Miltie

Continuing:

” Next we investigated the therapeutic potential of these neutralizing antibodies in a murine sepsis model. Injection of a lethal dose of LPS induced mortality in 90% of mice by 48 h. Neutralization of TNF-α alone or IFN-γ alone provided some protection, but combined neutralization of TNF-α and IFN-γ provided 94% protection against LPS-induced lethality (Figure 7D). These in vivo models suggest that TNF-α and IFN-γ–mediated inflammatory cell death, PANoptosis, drives pathology in not only COVID-19, but also other diseases and syndromes associated with cytokine storm, including cytokine shock, sepsis, and HLH. “


18 posted on 11/24/2020 4:27:48 PM PST by Uncle Miltie (Biden: Senile, pedophile, grifter, extortionist, thief.)
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To: Uncle Miltie

Hells bells, here’s a list of TNF alfa inhibitors:

https://www.drugs.com/drug-class/tnf-alfa-inhibitors.html


19 posted on 11/24/2020 4:30:36 PM PST by Uncle Miltie (Biden: Senile, pedophile, grifter, extortionist, thief.)
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