Posted on 09/08/2020 7:26:14 AM PDT by BenLurkin
Soon after SARS-CoV-2 was detected in China, researchers began analysing viral samples and posting the genetic codes online. Mutations — most of them single-letter alterations between viruses from different people — allowed researchers to track the spread by linking closely related viruses, and to estimate when SARS-CoV-2 started infecting humans.
Viruses that encode their genome in RNA, such as SARS-CoV-2, HIV and influenza, tend to pick up mutations quickly as they are copied inside their hosts, because enzymes that copy RNA are prone to making errors. After the severe acute respiratory syndrome (SARS) virus began circulating in humans, for instance, it developed a kind of mutation called a deletion that might have slowed its spread4.
But sequencing data suggest that coronaviruses change more slowly than most other RNA viruses, probably because of a ‘proofreading’ enzyme that corrects potentially fatal copying mistakes. A typical SARS-CoV-2 virus accumulates only two single-letter mutations per month in its genome — a rate of change about half that of influenza and one-quarter that of HIV, says Emma Hodcroft, a molecular epidemiologist at the University of Basel, Switzerland.
Other genome data have emphasized this stability — more than 90,000 isolates have been sequenced and made public... Two SARS-CoV-2 viruses collected from anywhere in the world differ by an average of just 10 RNA letters out of 29,903...
Many mutations will have no consequence for the virus’s ability to spread or cause disease, because they do not alter the shape of a protein, whereas those mutations that do change proteins are more likely to harm the virus than improve it (see ‘A catalogue of coronavirus mutations’). “It’s much easier to break something than it is to fix it,” says Hodcroft, who is part of Nextstrain, an effort to analyse SARS-CoV-2 genomes in real time.
(Excerpt) Read more at nature.com ...
Meh. Make sure plenty of zinc gets in your cells and you’ll be fine.
(Yawn)
My stomach can’t tolerate zinc supplements. Sorry to say. But as for the mutations, my understanding was that current vaccine development was focused toward a “base” or foundation of sorts that can be reengineered toward future mutations. It’s been several months since I read that so I can’t provide the link, or I would.
Similar to the flu vaccine....which I also get every year. :)
Knowledge.
Unh!
What is it good for?
(Yawn)
/Edwin Starr
You probably get plenty of Zinc in your food. But getting it INTO the cells can be the trick. Coffee does it. So does HCQ, and a lot of other foods. Just google it.
RNA really hates zinc, and the feeling is mutual.
It only matters if you are trying to sell a vaccine.
Viruses gonna virus.
It’s what they do.
Been doin’ it since The Beginning.
Well, you could be right, time will tell. I'll get both annually if necessary.
We’ll have a vaccine in less than two months. How do I know? Because the Dems are frantically trying to tell people that the trials are rushed and the FDA is crooked so as to blunt the WORLDWIDE CELEBRATION FOR TRUMP’S SUCCESS when it is released.
Nobody knows anything about COVID-19, except that it doesn’t behave like ny other virus ever known by medical science. It can kill up to 3 % of those infected, even though it decides to only kill .2%. It can infect someone 2 or 3 times because the human immune system can’t make antibodies for it even after a vaccine is developed, and any antibodies made don’t work like they do on every other known virus. It can be transmitted by droplets in the air that can remain suspended for hours, it can’t be killed by sunlight. It can spread over vast distances, even through masks and rubber gloves. It is so insidious that you can catch it and never know you had it because it can infect you without causing any symptoms. This way it can be spread around a population multiple times without killing people until maybe the third or fourth time they get it. Everyone can catch it ven when everyone has already had it and either died or recovered. Actually the one thing that is known about COVID-19 is that you can become immune to it by dying. That’s why so few people are immune.
“enzymes copying RNA are PRONE TO MAKING ERRORS”...the arrogance of assuming that “enzymes” are supposed to copy the virus exactly as our researchers see it amplifies the ignorance of these people. I do not have a PHD but I am wise enough to not question Gods creation.
Of course it is “mutating”, it is replicating. What they do not want you to know is that there is always a slight mistake in replication, and very rarely is that “mutation” a benefit for the virus.
Always a mistake in replication =
A progressively changed virus =
A progressively weaker virus
Then why not take a zinc ionaphore along with zinc to minimize the possibility of catching the virus? (Quercetin, selenium, green tea extract...)
And get doses of HCQ that are kept in the medicine cabinet to take the 5 day Zelenko protocol if you do become infected?
Doing these things makes a potentially dangerous vaccine unnecessary.
Mutation is adaptation. If the virus kills the host it won’t be able to spread. Natural selection is at work. The virus that doesn’t kill the host, spreads. Thus all of the subsequent viruses are less destructive to their hosts. The only hosts that die are the weak ones. Eventually only the weakest hosts will die. Pretty much what is already happening.
@ post 17
Bravo.
The coronavirus is mutating — does it matter?
“ Viruses that encode their genome in RNA, such as SARS-CoV-2, HIV and influenza, tend to pick up mutations quickly
as they are copied inside their hosts, because enzymes that copy RNA are prone to making errors.
After the severe acute respiratory syndrome (SARS) virus began circulating in humans, for instance,
it developed a kind of mutation called a deletion that might have slowed its spread."
"But sequencing data suggest that coronaviruses change more slowly than most other RNA viruses,
probably because of a ‘proofreading’ enzyme that corrects potentially fatal copying mistakes.
A typical SARS-CoV-2 virus accumulates only two single-letter mutations per month in its genome — a rate of change about half that of influenza and one-quarter that of HIV ...”
My Comment : The blessing of mutations is that the mutations tend to slow and self-limit the virus,
that is that they are self-detrimental .
The mutations change the efficacy of the virus, and in fact, generally weaken it.
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